2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-

Base Information

• Chemical Name: 2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-
• CAS No.: 94997-16-7
• Molecular Formula: C18H21NO3
• Molecular Weight: 299.37
• DSSTox Substance ID: DTXSID10461744
• Nikkaji Number: J1.003.703D
• Wikidata: Q82286146

Synonyms:94997-16-7;2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-;1-[2-(3,4-dimethoxyphenyl)ethyl]-5,6-dihydro-4H-indol-2-one;DTXSID10461744;AKOS025119992;BB 0269644

Chemical Property of 2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 299.15214353
• Heavy Atom Count: 22
• Complexity: 483

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CCN2C3=CCCCC3=CC2=O)OC

Technology Process of 2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-

There total 14 articles about 2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) + (2-oxo-1-phenylsulfanylcyclohexyl)-acetic acid ethyl ester (651315-16-1) → 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-2H-indol-2-one (94997-16-7)

Guidance literature:

2-(3,4-dimethoxyphenyl)-ethylamine; (2-oxo-1-phenylsulfanylcyclohexyl)-acetic acid ethyl ester; In toluene; for 3h; Heating;

With trifluoroacetic acid; In toluene; for 48h; Heating;

DOI:10.1021/jo048647f

Reference yield: 20.0%

1-(3,4-dimethoxyphenethyl)-4,5,6,7-tetrahydro-1H-indole → 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-2H-indol-2-one (94997-16-7)

Guidance literature:

With Dess-Martin periodane; at 0 - 20 ℃; for 1h;

DOI:10.1002/chem.201600273

Reference yield:

2,2,2-trichloro-N-cyclohex-1-enyl-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-acetamide (219740-93-9) → 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-2H-indol-2-one (94997-16-7)

Guidance literature:

With sodium acetate; acetic acid; nickel; In isopropyl alcohol; Heating;

DOI:10.1021/jo020573p

upstream raw materials:

1-(3,4-dimethoxy-phenethyl)-1,3,3a,4,5,6-hexahydro-indol-2-one

selenium(IV) oxide

ethanol

2,2,2-trichloro-N-cyclohex-1-enyl-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-acetamide

Downstream raw materials:

7-bromo-1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-2H-indol-2-one

(+/-)-3α,15,16-trimethoxy-8-oxo-Δ^1,6-erythrinan

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 94997-16-7 2H-Indol-2-one, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,4,5,6-tetrahydro-

Send

Send

Metric Ton KG G Pound L ML

Send

Send