Technology Process of Bis(2-phenylethyl)mercury
There total 4 articles about Bis(2-phenylethyl)mercury which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium chloride;
In
tetrahydrofuran; N,N-dimethyl-formamide;
addn. of soln. of C6H5CH2ZnBr in DMF to soln. of CuCN (20 mmol) and LiCl (40 mmol) in mixt. of dry DMF and dry THF at -40°C; warming suspension to 0°C, cooling to -60°C after 5 min; addn. of (ICH2)2Hg (3 mmol) from powder funnel;; addn. of methanol after 15 h at -60°C; workup after warming to 0°C; purification of crude product by flash chromy. (hexane); purity 95% (impurities: 2% (C6H5CH2)2Hg and 2% (C6H5CH2CH2CH2)2Hg);;
DOI:10.1016/0022-328X(92)88002-Z
- Guidance literature:
-
In
tetrahydrofuran; diethyl ether;
byproducts: MgClBr; soln. of Grignard compound in diethyl ether added to soln. of HgCl2 in THF at -78°C under Ar, warmed to room temp. stirred for 2 d; at -78°C water added, org. phase separated, washed (water), driedwith Na2SO4, solvent removed in vacuum (0.1 Torr, 50°C);
DOI:10.1002/1099-0682(200211)2002:11<2868::AID-EJIC2868>3.0.CO;2-S
- Guidance literature:
-
With
mercury dichloride;
In
diethyl ether;
