2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one

Base Information

Chemical Name:2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one
CAS No.:95728-57-7
Molecular Formula:C10H8BrF3O
Molecular Weight:281.072
Hs Code.:2914790090
European Community (EC) Number:871-368-5
DSSTox Substance ID:DTXSID40439714
Nikkaji Number:J1.882.242C
Mol file:95728-57-7.mol

Synonyms:95728-57-7;2-BROMO-1-(4-(TRIFLUOROMETHYL)PHENYL)PROPAN-1-ONE;2-bromo-1-[4-(trifluoromethyl)phenyl]propan-1-one;2-Bromo-4'-(trifluoromethyl)propiophenone;2-Bromo-1-(4-trifluoromethyl-phenyl)-propan-1-one;SCHEMBL786834;DTXSID40439714;VDA72857;MFCD17010234;AS-35452;CS-0199794;4'-(Trifluoromethyl)-alpha-bromopropiophenone;EN300-3361578;2-Bromo-1-[4-(trifloromethyl)phenyl-1-propanone;A922858

Suppliers and Price of 2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Bromo-4'-(trifluoromethyl)propiophenone
250 mg
$ 80.00

SynQuest Laboratories
2-Bromo-4'-(trifluoromethyl)propiophenone
1 g
$ 240.00

SynQuest Laboratories
2-Bromo-4'-(trifluoromethyl)propiophenone
5 g
$ 720.00

Matrix Scientific
2-Bromo-1-(4-trifluoromethyl-phenyl)-propan-1-one 95%+
1g
$ 447.00

AstaTech
2-BROMO-1-(4-(TRIFLUOROMETHYL)PHENYL)PROPAN-1-ONE 95%
5 / G
$ 780.00

AstaTech
2-BROMO-1-(4-(TRIFLUOROMETHYL)PHENYL)PROPAN-1-ONE 95%
1 / G
$ 260.00

AstaTech
2-BROMO-1-(4-(TRIFLUOROMETHYL)PHENYL)PROPAN-1-ONE 95%
0.25 / G
$ 104.00

Apolloscientific
2-Bromo-4'-(trifluoromethyl)propiophenone
1g
$ 149.00

Apolloscientific
2-Bromo-4'-(trifluoromethyl)propiophenone
250mg
$ 50.00

Apolloscientific
2-Bromo-4'-(trifluoromethyl)propiophenone
5g
$ 450.00

Total 6 raw suppliers

Chemical Property of 2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one

Chemical Property:

PSA：17.07000
LogP:3.67150
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:279.97106
Heavy Atom Count:15
Complexity:231

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-4'-(trifluoromethyl)propiophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C1=CC=C(C=C1)C(F)(F)F)Br

Technology Process of 2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one

There total 4 articles about 2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 711-33-1
4-trifluoromethyl propiophenone

: 95728-57-7
2-bromo-1-(4-trifluoromethylphenyl)propan-1-one

Guidance literature:: With bromine; acetic acid; at 40 ℃; for 2.5h;
DOI:10.1021/jm00020a005

Reference yield:

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 95728-57-7
2-bromo-1-(4-trifluoromethylphenyl)propan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether

2: CrO₃; H₂SO₄ / acetone; H₂O / 10 °C

3: 48percent HBr; Br₂ / CH₂Cl₂; H₂O / 35 °C

With chromium(VI) oxide; sulfuric acid; bromine; In diethyl ether; dichloromethane; water; acetone; 1: Grignard addition / 2: Jones oxidation;
DOI:10.1021/jo011042o

Reference yield:

: 67081-98-5
(+/-)-1-<4-(trifluoromethyl)phenyl>-1-propanol

: 95728-57-7
2-bromo-1-(4-trifluoromethylphenyl)propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: CrO₃; H₂SO₄ / acetone; H₂O / 10 °C

2: 48percent HBr; Br₂ / CH₂Cl₂; H₂O / 35 °C

With chromium(VI) oxide; sulfuric acid; bromine; In dichloromethane; water; acetone; 1: Jones oxidation;
DOI:10.1021/jo011042o