Technology Process of (Z)-1-Bromo-1,2-diphenyl-1-butene
There total 8 articles about (Z)-1-Bromo-1,2-diphenyl-1-butene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bromine; sodium methylate;
In
methanol; dichloromethane;
at -78 - 20 ℃;
for 2h;
DOI:10.1021/jo00212a023
- Guidance literature:
-
diphenylzinc;
With
diethylzinc;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; toluene;
at 15 - 20 ℃;
Inert atmosphere;
Large scale reaction;
1-phenyl-1-butyne;
With
bis(acetylacetonate)nickel(II);
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; toluene;
at -5 - 20 ℃;
Inert atmosphere;
Large scale reaction;
With
1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; toluene;
at -10 - 20 ℃;
optical yield given as %de;
stereoselective reaction;
Inert atmosphere;
Large scale reaction;
DOI:10.1021/op100112r
- Guidance literature:
-
ethyllithium; diphenyl acetylene;
In
tetrahydrofuran; dibutyl ether;
at -10 ℃;
for 2h;
With
ethylene dibromide;
In
tetrahydrofuran; dibutyl ether;
at -78 ℃;
DOI:10.1021/jo061949s
