1-(4-Fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole

Base Information

Chemical Name:1-(4-Fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole
CAS No.:96757-48-1
Molecular Formula:C22H22FN
Molecular Weight:319.422
Hs Code.:
DSSTox Substance ID:DTXSID80542872
Wikidata:Q82419667

Synonyms:1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole;96757-48-1;DTXSID80542872

Suppliers and Price of 1-(4-Fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole

Chemical Property:

XLogP3:6.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:319.173627868
Heavy Atom Count:24
Complexity:420

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCC2=C(C1)N(C(=C2)C3=CC=CC=C3)C4=CC=C(C=C4)F)C

Technology Process of 1-(4-Fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole

There total 4 articles about 1-(4-Fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1h-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96757-46-9
1-(4-Fluoro-phenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1H-indol-4-ol

: 96757-48-1
1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1H-indole

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 50 ℃; for 8h;

Reference yield:

: 96757-23-2
1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one

: 96757-48-1
1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 28 g / LAH / tetrahydrofuran / 5 h / Heating

2: 1.8 g / H₂ / 10percent Pd/C / tetrahydrofuran / 8 h / 50 °C

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran;

Reference yield:

: 371-40-4
4-fluoroaniline

: 96757-48-1
1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 2 h / 170 - 180 °C

2: 28 g / LAH / tetrahydrofuran / 5 h / Heating

3: 1.8 g / H₂ / 10percent Pd/C / tetrahydrofuran / 8 h / 50 °C

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran;