6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide

Base Information

Chemical Name:6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide
CAS No.:96759-26-1
Molecular Formula:C13H22BrNO
Molecular Weight:288.228
Hs Code.:
DSSTox Substance ID:DTXSID70542907

Synonyms:96759-26-1;6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide;DTXSID70542907;6-bromo-N,N-diisopropyl-cyclohexene-1-carboxamide;6-bromo-N,N-diisopropyl-1-cyclohexene-1-carboxamide

Suppliers and Price of 6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:287.08848
Heavy Atom Count:16
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N(C(C)C)C(=O)C1=CCCCC1Br

Technology Process of 6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide

There total 3 articles about 6-Bromo-N,N-di(propan-2-yl)cyclohex-1-ene-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 636-82-8
cyclohexene-1-carboxylic acid

: 96759-26-1
N,N-diisopropyl-6-bromo-1-cyclohexenecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 2.5 h / Heating

2: diethyl ether / 4 h / Ambient temperature

3: 1.) sec-BuLi, TMEDA, trimethylborate; 2.) Br₂ / 1.) THF, -78 deg C, 20 min; -78 deg C to 0 deg C, 1 h; 2.) THF, 0.5 h, RT

With thionyl chloride; Trimethyl borate; N,N,N,N,-tetramethylethylenediamine; bromine; sec.-butyllithium; In diethyl ether;
DOI:10.1021/ja00302a024

Reference yield:

: 36278-22-5
1-cyclohexenoyl chloride

: 96759-26-1
N,N-diisopropyl-6-bromo-1-cyclohexenecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 4 h / Ambient temperature

2: 1.) sec-BuLi, TMEDA, trimethylborate; 2.) Br₂ / 1.) THF, -78 deg C, 20 min; -78 deg C to 0 deg C, 1 h; 2.) THF, 0.5 h, RT

With Trimethyl borate; N,N,N,N,-tetramethylethylenediamine; bromine; sec.-butyllithium; In diethyl ether;
DOI:10.1021/ja00302a024

Reference yield:

: 80997-37-1
N,N-diisopropyl-1-cyclohexenecarboxamide

: 96759-26-1
N,N-diisopropyl-6-bromo-1-cyclohexenecarboxamide

Guidance literature:: With Trimethyl borate; N,N,N,N,-tetramethylethylenediamine; bromine; sec.-butyllithium; Yield given. Multistep reaction; 1.) THF, -78 deg C, 20 min; -78 deg C to 0 deg C, 1 h; 2.) THF, 0.5 h, RT;
DOI:10.1021/ja00302a024