N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide

Base Information

Chemical Name:N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide
CAS No.:97637-06-4
Molecular Formula:C16H19NO4S
Molecular Weight:321.397
Hs Code.:
DSSTox Substance ID:DTXSID20709785
Wikidata:Q82644906

Synonyms:97637-06-4;SCHEMBL5622498;DTXSID20709785;PVYAGTUYJKNYFM-UHFFFAOYSA-N;N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide;N-Ethyl-4-methoxy-N-(4-methoxy-phenyl)-benzenesulfonamide

Suppliers and Price of N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:321.10347926
Heavy Atom Count:22
Complexity:418

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(C1=CC=C(C=C1)OC)S(=O)(=O)C2=CC=C(C=C2)OC

Technology Process of N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide

There total 4 articles about N-Ethyl-4-methoxy-N-(4-methoxyphenyl)benzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 24924-59-2
4-methoxy-N-(4-methoxyphenyl)benzenesulfonamide

: 97637-06-4
N-(4-methoxyphenyl)-N-(ethyl)-4-methoxybenzene sulfonamide

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; water; at 20 ℃; for 12h;
DOI:10.1016/S0968-0896(00)00075-4

Reference yield: 75.0%

: 97637-06-4
N-(4-methoxyphenyl)-N-(ethyl)-4-methoxybenzene sulfonamide

Guidance literature:

Reference yield:

: 104-94-9
4-methoxy-aniline

: 97637-06-4
N-(4-methoxyphenyl)-N-(ethyl)-4-methoxybenzene sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / pyridine / CH₂Cl₂ / 20 °C

2: 86 percent / NaOH; (n-Bu)4NSO₄H / H₂O; CH₂Cl₂ / 12 h / 20 °C

With pyridine; sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; water; 1: sulfonylation / 2: Alkylation;
DOI:10.1016/S0968-0896(00)00075-4