4-Difluoromethoxy-2-nitro-aniline

Base Information

Chemical Name:4-Difluoromethoxy-2-nitro-aniline
CAS No.:97963-76-3
Molecular Formula:C7H6F2N2O3
Molecular Weight:204.133
Hs Code.:2921420090
Mol file:97963-76-3.mol

Synonyms:4-difluoromethoxy-2-nitroaniline;2-Amino-5-diaethylamino-phenol;2-amino-5-difluoromethoxynitrobenzene;Phenol,2-amino-5-(diethylamino);2-amino-5-diethylamino-phenol;

Suppliers and Price of 4-Difluoromethoxy-2-nitro-aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-(Difluoromethoxy)-2-nitroaniline 97%
250 mg
$ 136.00

Labseeker
Benzenamine,4-(difluoromethoxy)-2-nitro- 95
5g
$ 2083.00

American Custom Chemicals Corporation
4-DIFLUOROMETHOXY-2-NITROPHENYLAMINE 95.00%
5G
$ 909.56

Ambeed
4-(Difluoromethoxy)-2-nitroaniline 97%
250mg
$ 84.00

Ambeed
4-(Difluoromethoxy)-2-nitroaniline 97%
100mg
$ 45.00

Ambeed
4-(Difluoromethoxy)-2-nitroaniline 97%
1g
$ 166.00

Alichem
4-(Difluoromethoxy)-2-nitroaniline
1g
$ 1534.70

Alichem
4-(Difluoromethoxy)-2-nitroaniline
500mg
$ 806.85

Alichem
4-(Difluoromethoxy)-2-nitroaniline
250mg
$ 480.00

Total 12 raw suppliers

Chemical Property of 4-Difluoromethoxy-2-nitro-aniline

Chemical Property:

Boiling Point:330.0±37.0 °C(Predicted)
PKA:-0.74±0.10(Predicted)
PSA：81.07000
Density:1.470±0.06 g/cm3(Predicted)
LogP:2.88280
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

4-(Difluoromethoxy)-2-nitroaniline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-(Difluoromethoxy)-2-nitroaniline is a useful reagent used in the preparation of 2-mercapto-5-difluoromethoxy-1H-benzimidazole; an important medicinal intermediate.

Technology Process of 4-Difluoromethoxy-2-nitro-aniline

There total 4 articles about 4-Difluoromethoxy-2-nitro-aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 97963-75-2
N-[(4-difluoromethoxy-2-nitro)phenyl]-acetamide

: 97963-76-3
4-difluoromethoxy-2-nitroaniline

Guidance literature:: With sodium hydroxide; water; at 60 ℃; for 1.5h;

Reference yield: 96.0%

: 97963-76-3
4-difluoromethoxy-2-nitroaniline

Guidance literature:

Reference yield:

: 103-90-2,8055-08-1
4-acetaminophenol

: 97963-76-3
4-difluoromethoxy-2-nitroaniline

Guidance literature:: Multi-step reaction with 3 steps

1: PEG-600 / 50 - 55 °C

2: nitric acid; sulfuric acid / 2 h / 20 - 25 °C

3: methanol / 3 h / Reflux

With sulfuric acid; nitric acid; In methanol;
DOI:10.14233/ajchem.2013.14818