2,3-Bis(hydroxymethyl)-1-methylpyrrole

Base Information

Chemical Name:2,3-Bis(hydroxymethyl)-1-methylpyrrole
CAS No.:53365-77-8
Molecular Formula:C₇H₁₁NO₂
Molecular Weight:141.17
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90201529
Nikkaji Number:J87.073K
Wikidata:Q83074738
Mol file:53365-77-8.mol

Synonyms:2,3-bis(hydroxymethyl)-1-methylpyrrole;bis(hydroxymethyl)-1-methylpyrrole

Suppliers and Price of 2,3-Bis(hydroxymethyl)-1-methylpyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3-BIS(HYDROXYMETHYL)-1-METHYLPYRROLE 95.00%
5MG
$ 505.41

Total 4 raw suppliers

Chemical Property of 2,3-Bis(hydroxymethyl)-1-methylpyrrole

Chemical Property:

Vapor Pressure:0.000191mmHg at 25°C
Refractive Index:1.4300 (estimate)
Boiling Point:315°Cat760mmHg
Flash Point:144.3°C
PSA：45.39000
Density:1.16g/cm³
LogP:0.00970
XLogP3:-1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:141.078978594
Heavy Atom Count:10
Complexity:108

Purity/Quality:

99% ^*data from raw suppliers

2,3-BIS(HYDROXYMETHYL)-1-METHYLPYRROLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=CC(=C1CO)CO

Technology Process of 2,3-Bis(hydroxymethyl)-1-methylpyrrole

There total 5 articles about 2,3-Bis(hydroxymethyl)-1-methylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 25472-58-6
Dimethyl 1-methyl-1H-pyrrole-2,3-dicarboxylate

: 53365-77-8
2,3-bis(hydroxymethyl)-1-methylpyrrole

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 1.5h; Heating;
DOI:10.1021/ja00062a002

Reference yield:

: 161677-79-8
(2E,4E,6E)-diethyl 3,6-dicyano-2,7-dihydroxyocta-2,4,6-trienedioate

: 53365-77-8
2,3-bis(hydroxymethyl)-1-methylpyrrole

Guidance literature:: Multi-step reaction with 4 steps

1: 48 percent / ethyl acetate; H₂O; ethanol / 4 h / Heating

2: 98 percent / aq. NaOH / 6.5 h / 135 °C

3: 94 percent / trimethylsilyl chloride / 24 h / 25 °C

4: 100 percent / LiAlH₄ / diethyl ether / 1.5 h / Heating

With sodium hydroxide; lithium aluminium tetrahydride; chloro-trimethyl-silane; In diethyl ether; ethanol; water; ethyl acetate;
DOI:10.1021/ja00062a002

Reference yield:

: 7164-21-8
2-carbethoxy-3-cyano-1-methylpyrrole

: 53365-77-8
2,3-bis(hydroxymethyl)-1-methylpyrrole

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / aq. NaOH / 6.5 h / 135 °C

2: 94 percent / trimethylsilyl chloride / 24 h / 25 °C

3: 100 percent / LiAlH₄ / diethyl ether / 1.5 h / Heating

With sodium hydroxide; lithium aluminium tetrahydride; chloro-trimethyl-silane; In diethyl ether;
DOI:10.1021/ja00062a002