Camphidine

Base Information

• Chemical Name: Camphidine
• CAS No.: 49707-52-0
• Molecular Formula: C15H23 N
• Molecular Weight: 217.354
• DSSTox Substance ID: DTXSID30275966
• Nikkaji Number: J100.069A
• Wikidata: Q82006247
• Mol file: 49707-52-0.mol

Synonyms:camphidine

Chemical Property of Camphidine

Chemical Property:

• Vapor Pressure: 0.00284mmHg at 25°C
• Boiling Point: 294.5°Cat760mmHg
• Flash Point: 123.8°C
• PSA: 12.36000
• Density: 0.84g/cm³
• LogP: 4.32030
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 153.151749610
• Heavy Atom Count: 11
• Complexity: 174

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1(C2CCC1(CNC2)C)C
• Isomeric SMILES: C[C@@]12CC[C@@H](C1(C)C)CNC2

Technology Process of Camphidine

There total 7 articles about Camphidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

tert-Octylamine (107-45-9) + benzaldehyde (100-52-7) → 1-phenyl-N-(2,4,4-trimethylpentan-2-yl)methanimine (49707-52-0)

Guidance literature:

In benzene; Heating;

DOI:10.1021/jo00153a033

Reference yield: 80.0%

tert-Octylamine (107-45-9) + benzyl alcohol (100-51-6,185532-71-2) → 1-phenyl-N-(2,4,4-trimethylpentan-2-yl)methanimine (49707-52-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; [RuCl₂(IiPr)(p-cymene)]; In toluene; for 24h; Inert atmosphere; Molecular sieve; Reflux;

DOI:10.1021/om201095m

Reference yield: 35.0%

tert-Octylamine (107-45-9) + benzyl alcohol (100-51-6,185532-71-2) → 1-phenyl-N-(2,4,4-trimethylpentan-2-yl)methanimine (49707-52-0) + benzyl-(1,1,3,3-tetramethyl-butyl)-amine (3598-75-2)

Guidance literature:

With (p-cymene)ruthenium(II) chloride; In toluene; for 24h; Inert atmosphere; Molecular sieve; Reflux;

DOI:10.1021/om201095m

upstream raw materials:

tert-Octylamine

benzaldehyde

benzyl alcohol

5,5-dimethylhexan-1-amine

Downstream raw materials:

N-(2,4,4-trimethylpentan-2-yl)benzamide

benzyl-(1,1,3,3-tetramethyl-butyl)-amine

3-Phenyl-2-tert-octyloxazirane

Refernces

• 1、 Li, Xiao-Gen,Zhou, Qi-Lin. "Manganese-Catalyzed Selective Hydrogenative Cross-Coupling of Nitriles and Amines to Form Secondary Imines". supporting information. p. 3471 - 3475. Retrieved 2021/04/29.
• 2、 Janzen, Edward G.,Nutter, Dale E.. "Spin trapping chemistry of iminyl free radicals". . p. 131 - 140. Retrieved 2007/10/03.