(4-(Hydroxyamino)phenyl)methanol

Base Information

• Chemical Name: (4-(Hydroxyamino)phenyl)methanol
• CAS No.: 99237-42-0
• Molecular Formula: C7H9NO2
• Molecular Weight: 139.154
• DSSTox Substance ID: DTXSID60573760
• Nikkaji Number: J1.355.821C
• Wikidata: Q82462580
• Mol file: 99237-42-0.mol

Synonyms:(4-(hydroxyamino)phenyl)methanol;99237-42-0;[4-(Hydroxyamino)phenyl]methanol;SCHEMBL5827700;DTXSID60573760

Chemical Property of (4-(Hydroxyamino)phenyl)methanol

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 139.063328530
• Heavy Atom Count: 10
• Complexity: 89.6

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CO)NO

Technology Process of (4-(Hydroxyamino)phenyl)methanol

There total 3 articles about (4-(Hydroxyamino)phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

4-nitrobenzyl chloride (619-73-8) → 4-(hydroxyamino)benzyl alcohol (99237-42-0)

Guidance literature:

With ammonium chloride; zinc; In 2-methoxy-ethanol; water; at 20 ℃; for 0.25h;

DOI:10.1080/15257770802400099

Reference yield:

4-nitrobenzaldehdye (555-16-8) → 4-aminobenzaldehyde (556-18-3,28107-09-7) + 4-aminobenzenemethanol (623-04-1) + 4-hydroxyamino-benzaldehyde (86233-65-0) + 4-(hydroxyamino)benzyl alcohol (99237-42-0)

Guidance literature:

In ethanol; water; at 25 ℃; Rate constant; Mechanism; Product distribution; polarographic reduction; potential dependent rate constanzs k_f,h, αn_a; pH = 1.81-11.00;

Reference yield:

4-nitrobenzyl chloride (619-73-8) + water (7732-18-5) → 4-(hydroxyamino)benzyl alcohol (99237-42-0)

Guidance literature:

upstream raw materials:

4-nitrobenzyl chloride

4-nitrobenzaldehdye

water

Downstream raw materials:

4,4’-bis(hydroxymethyl)azoxybenzene

(4-nitrosophenyl)methanol