Ethanimidic acid, 2,2,2-trichloro-, 1-phenylethyl ester

Base Information

• Chemical Name: Ethanimidic acid, 2,2,2-trichloro-, 1-phenylethyl ester
• CAS No.: 99421-72-4
• Molecular Formula: C10H10Cl3NO
• Molecular Weight: 266.554
• Mol file: 99421-72-4.mol

Synonyms:

Chemical Property of Ethanimidic acid, 2,2,2-trichloro-, 1-phenylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanimidic acid, 2,2,2-trichloro-, 1-phenylethyl ester

There total 3 articles about Ethanimidic acid, 2,2,2-trichloro-, 1-phenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Phenylethanol (98-85-1,13323-81-4) + trichloroacetonitrile (545-06-2) → 1-phenylethyl 2,2,2-trichloroacetimidate (99421-72-4)

Guidance literature:

With diethyl ether; sodium;

Reference yield:

(R)-1-phenylethanol (1517-69-7) + trichloroacetonitrile (545-06-2) → 1-phenylethyl 2,2,2-trichloroacetimidate (99421-72-4)

Guidance literature:

With diethyl ether; sodium;

Reference yield:

diethyl ether (60-29-7,927820-24-4) + (R)-1-phenylethanol (1517-69-7) → 1-phenylethyl 2,2,2-trichloroacetimidate (99421-72-4)

Guidance literature:

Erwaermen mit Trichloracetonitril;

upstream raw materials:

(R)-1-phenylethanol

trichloroacetonitrile

diethyl ether

1-Phenylethanol

Downstream raw materials:

C₈H₉⁽²⁾HO

benzyl 1-phenylethyl ether

2,4-dichloro-N-(1-phenylethyl)aniline

1-phenylethyl benzoate

Refernces

• 1、 Wallach, Daniel R.,Stege, Patrick C.,Shah, Jigisha P.,Chisholm, John D.. "Br?nsted acid catalyzed monoalkylation of anilines with trichloroacetimidates". . p. 1993 - 2000. Retrieved 2015/02/19.
• 2、 Zhang, Qi,Mixdorf, Jason C.,Reynders, Gilbert J.,Nguyen, Hien M.. "Rhodium-catalyzed benzylic fluorination of trichloroacetimidates". . p. 5932 - 5938. Retrieved 2015/08/03.