5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

Base Information

Chemical Name:5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one
CAS No.:28495-91-2
Molecular Formula:C13H14 N2 O2 S
Molecular Weight:262.3275
Hs Code.:
NSC Number:211570
DSSTox Substance ID:DTXSID00397765
Nikkaji Number:J696.896A

Synonyms:28495-91-2;NSC211570;SCHEMBL11450502;DTXSID00397765;5-[3-Ethoxybenzyl]-2-thiouracil;NSC-211570;5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

Suppliers and Price of 5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.29g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:262.07759887
Heavy Atom Count:18
Complexity:368

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=CC(=C1)CC2=CNC(=S)NC2=O

Technology Process of 5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

There total 5 articles about 5-[(3-Ethoxyphenyl)methyl]-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24393-57-5
3-(3-ethoxy-phenyl)-acrylic acid ethyl ester

: 28495-91-2
5-(3-ethoxy-benzyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / 5percent Pd/C / ethanol

2: sodium wire / diethyl ether / 18 h / Ambient temperature

3: ethanol / 7 h / Heating

With hydrogen; sodium; palladium on activated charcoal; In diethyl ether; ethanol;
DOI:10.1016/0223-5234(88)90167-5

Reference yield:

: 34708-60-6
3-(3-hydroxy-phenyl)propionic acid ethyl ester

: 28495-91-2
5-(3-ethoxy-benzyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetone

2: 1.) Na, 3.) conc. HCl

With hydrogenchloride; sodium; potassium carbonate; In acetone;
DOI:10.1021/jm00019a015

Reference yield:

: 116609-01-9
3-(3-ethoxy-phenyl)-propionic acid ethyl ester

: 28495-91-2
5-(3-ethoxy-benzyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium wire / diethyl ether / 18 h / Ambient temperature

2: ethanol / 7 h / Heating

With sodium; In diethyl ether; ethanol;
DOI:10.1016/0223-5234(88)90167-5