4-Bromo-6-methylpicolinic acid

Base Information

Chemical Name:4-Bromo-6-methylpicolinic acid
CAS No.:886372-47-0
Molecular Formula:C7H6BrNO2
Molecular Weight:216.034
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00704490
Wikidata:Q82636927
Mol file:886372-47-0.mol

Synonyms:4-Bromo-6-methylpicolinic acid;886372-47-0;4-Bromo-6-methylpyridine-2-carboxylic acid;4-BROMO-6-METHYL-PYRIDINE-2-CARBOXYLIC ACID;4-Bromo-6-methylpicolinicacid;SCHEMBL1424923;DTXSID00704490;IQFWXNNNXVXOBJ-UHFFFAOYSA-N;AB40781;AS-77014;CS-0186962;FT-0753942;D95055;A849351

Suppliers and Price of 4-Bromo-6-methylpicolinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-6-methyl-pyridine-2-carboxylicAcid
50mg
$ 200.00

SynChem
4-BROMO-6-METHYLPYRIDINE-2-CARBOXYLIC ACID 95%
1 g
$ 980.00

Chemenu
4-Bromo-6-methylpicolinicacid 95%
1g
$ 1094.00

Anichem
4-Bromo-6-methyl-pyridine-2-carboxylicacid >95%
1g
$ 680.00

Anichem
4-Bromo-6-methyl-pyridine-2-carboxylicacid >95%
1g
$ 680.00

American Custom Chemicals Corporation
4-BROMO-6-METHYLPICOLINIC ACID 95.00%
1G
$ 24332.70

American Custom Chemicals Corporation
4-BROMO-6-METHYLPICOLINIC ACID 95.00%
5MG
$ 502.32

Ambeed
4-Bromo-6-methylpicolinicacid 95%
250mg
$ 180.00

Ambeed
4-Bromo-6-methylpicolinicacid 95%
1g
$ 459.00

Ambeed
4-Bromo-6-methylpicolinicacid 95%
100mg
$ 98.00

Total 14 raw suppliers

Chemical Property of 4-Bromo-6-methylpicolinic acid

Chemical Property:

Boiling Point:339.6±42.0 °C(Predicted)
PKA:3.32±0.10(Predicted)
PSA：50.19000
Density:1.692±0.06 g/cm3(Predicted)
LogP:1.85070
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:214.95819
Heavy Atom Count:11
Complexity:163

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-6-methyl-pyridine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=N1)C(=O)O)Br

Technology Process of 4-Bromo-6-methylpicolinic acid

There total 1 articles about 4-Bromo-6-methylpicolinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5470-66-6
2-methyl-4-nitropyridine N-oxide

: 886372-47-0
4-bromo-6-methylpicolinic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: dimethyl sulfate / 2 h / 65 - 70 °C

1.2: 3.6 h / -10 °C / Inert atmosphere

2.1: sulfuric acid / 2 h / 120 °C

2.2: 2 h / 12 - 80 °C

3.1: hydrogen bromide / 100 °C

With sulfuric acid; hydrogen bromide; dimethyl sulfate;

Reference yield:

: 886372-47-0
4-bromo-6-methylpicolinic acid

: (4S,5S)-tert-butyl 4-((5-chloro-2-fluoro-4-(2-(4-(isopropylamino)-6-methylpicolinoyl)hydrazinecarbonyl)phenoxy)methyl)-2,2,5-trimethyloxazolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: butan-1-ol / 48 h / 117 °C

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl acetamide / 0.17 h / 20 °C

2.2: 2 h / 20 °C

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl acetamide; butan-1-ol;