3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol

Base Information

Chemical Name:3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol
CAS No.:104535-37-7
Molecular Formula:C₈H₉NO₂
Molecular Weight:151.165
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60598579
Nikkaji Number:J2.990.933D
Wikidata:Q72464639
Mol file:104535-37-7.mol

Synonyms:104535-37-7;3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol;3,4-dihydro-2H-1,4-benzoxazin-7-ol;2H-1,4-BENZOXAZIN-7-OL, 3,4-DIHYDRO-;3,4-DIHYDRO-2H-BENZO[1,4]OXAZIN-7-OL;MFCD11101010;SCHEMBL2746377;DTXSID60598579;OMQHSWHJETUHBX-UHFFFAOYSA-N;AKOS006307395;MB09266;2H-1,4-Benzoxazin-7-ol,3,4-dihydro;AS-53562;SY014537;DB-347799;AM20020138;CS-0270702;2,3-dihydro-7-hydroxy-4H-benzo[1,4]oxazine;P16674;EN300-2967067;A846705

Suppliers and Price of 3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Dihydro-2H-benzo[b][1,4]oxazin-7-ol
100mg
$ 200.00

Crysdot
3,4-Dihydro-2H-benzo[b][1,4]oxazin-7-ol 95+%
1g
$ 762.00

Chemenu
3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol 95%
1g
$ 720.00

Total 17 raw suppliers

Chemical Property of 3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol

Chemical Property:

Appearance/Colour:white powder
PSA：41.49000
Density:1.241
LogP:1.33450
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:151.063328530
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

3,4-Dihydro-2H-benzo[b][1,4]oxazin-7-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(N1)C=CC(=C2)O

Technology Process of 3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol

There total 4 articles about 3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 93735-22-9
7-methoxy-3,4-dihydro-2H-benzo-[b][1,4]oxazine

: 104535-37-7
7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine

Guidance literature:: With hydrogen bromide; for 2h; Heating;
DOI:10.1016/S0223-5234(99)00109-9

Reference yield:

: 67193-97-9
7-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one

: 104535-37-7
7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine

Guidance literature:: With borane-THF; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1021/jm701129j

Reference yield:

: 6529-94-8
7-methoxy-2H-1,4-benzoxazin-3-one

: 104535-37-7
7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / LiAlH₄ / tetrahydrofuran / 3 h / Heating

2: 85 percent / 62 percent HBr / 2 h / Heating

With lithium aluminium tetrahydride; hydrogen bromide; In tetrahydrofuran; 1: Reduction / 2: demethylation;
DOI:10.1016/S0223-5234(99)00109-9