6529-94-8

Usage

Uses

Used in Agricultural Applications:
7-Methoxy-2H-1,4-benzoxazin-3(4h)-one is used as a natural herbicide and pesticide for its ability to inhibit the growth and development of competing plants and pests. Its allelopathic properties make it a promising candidate for sustainable and eco-friendly weed and pest control in agriculture.
Used in Medical Applications:
7-Methoxy-2H-1,4-benzoxazin-3(4h)-one is used as a potential therapeutic agent for its anti-inflammatory, antifungal, and antioxidant properties. These properties make it a candidate for the development of new treatments for various medical conditions, including inflammation-related disorders and fungal infections.
Used in Research and Development:
7-Methoxy-2H-1,4-benzoxazin-3(4h)-one is used as a subject of scientific research to further explore its unique chemical structure and biological activities. 7-Methoxy-2H-1,4-benzoxazin-3(4h)-one's potential applications in agriculture and medicine have garnered significant interest in the scientific community, leading to ongoing studies and the development of new formulations and delivery systems to enhance its efficacy and safety.

Upstream product

• 72001-30-0 4-acetoxy-7-methoxy-(2H)-1,4-benzoxazin-3(4H)-one 
• 72594-77-5 N-(tert-butoxycarbonyl)-L-tyrosine ethyl ester 
• 72001-37-7 7-methoxy-4-(1-methyl-4-oxo-2,5-cyclohexadien-1-yl)-2H-1,4-benzoxazin-3(4H)-one 
• 31366-46-8 4-methoxy-2H-1,4-benzoxazin-3(4H)-one 
• 108-95-2 phenol 

Downstream Products

• 93735-22-9 7-methoxy-3,4-dihydro-2H-benzo-[b][1,4]oxazine 
• 6238-86-4 [2-(3,4-Dichloro-benzoylamino)-5-methoxy-phenoxy]-acetic acid 
• 104535-37-7 7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine 
• 258524-52-6 4-benzoyl-7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine 
• 1027218-05-8 (7-oxiranylmethoxy-2,3-dihydro-benzo[1,4]oxazin-4-yl)-phenyl-methanone 
• 6548-55-6 [2-(4-Chloro-benzoylamino)-5-methoxy-phenoxy]-acetic acid 
• 92963-37-6 4-benzoyl-7-methoxy-3,4-dihydro-2H-benzo[1,4]oxazine 

Relevant academic research and scientific papers

A multi-centered electrophile formed from a unique bioactive cyclic hydroxamic acid, 4-hydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one

4-Hydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (HMBOA) is a compound of considerable interest because of its pharmacological, agrochemical, and antimicrobial properties. A plausible bioactive metabolite of HMBOA is 4-acetoxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (AMBOA). Electrophilic reactions of AMBOA with phenols, anilines, thiols, heteroaromatics, amino acid derivatives and nucleic acids were investigated in relation to the chemical mechanisms of the biological effects elicited by the compound. The results suggest that HMBOA acts as an alkylating agent of proteins and nucleic acids in vivo after metabolic O-acylation.

A Simple Synthesis of 5-Methoxyindole and 5-Methoxy-2-oxindole

1-Methoxy- and 1-hydroxy-2-oxindoles rearranged in acidic solution to 5-substituted 2-aminophenylacetic acid derivatives which were cyclized to the corresponding 2-oxindoles with heating.The synthesis of 5-methoxyindole from 5-methoxy-2-oxindole was also described.

REACTION OF 4-ACETOXY-1,4-BENZOXAZIN-3-ONE WITH AMINO ACID DERIVATIVES

A reaction of 4-acetoxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (2) with t-butoxycarbonyl-L-tyrosine ethyl ester (Boc-L-Tyr-OEt), t-butoxycarbonyl-L-histidine methyl ester (Boc-L-His-OMe) and t-butoxycarbonyl-L-tryptophan methyl ester (Boc-L-Trp-OMe) was described.The 4 and 6 positions in the benzoxazinone ring were attacked by the amino acids.The reaction with Boc-L-Trp-OMe gave hexahydropyrroloindoles.