hydrochloride

Base Information

• Chemical Name: hydrochloride
• CAS No.: 84182-59-2
• Molecular Formula: C₅H₉NO₂*ClH
• Molecular Weight: 151.593
• Hs Code.: 2922499990
• Mol file: 84182-59-2.mol

Synonyms:hydrochloride;

Chemical Property of hydrochloride

Chemical Property:

• PSA: 63.32000
• LogP: 1.31060
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-3-Aminocyclobutane-1-carboxylic acid hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of hydrochloride

There total 9 articles about hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

hydrochloride of amide of cis-3-aminocyclobutane-1-carboxylic acid (84182-57-0) → hydrochloride of cis-3-aminocyclobutane-1-carboxylic acid (84182-59-2)

Guidance literature:

With hydrogenchloride; In water; for 20h; Heating;

Reference yield:

methylester of 3-hydroxycyclobutane-1-carboxylic acid (4934-99-0) → hydrochloride of cis-3-aminocyclobutane-1-carboxylic acid (84182-59-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 88 percent / pyridine / 336 h

2: 80 percent / NH₄Br, NH₃ / 144 h / Ambient temperature

3: 59 percent / NaN₃ / methanol; H₂O / 20 h / Heating

4: 81 percent / H₂ / PtO₂ / methanol / 6 h / Ambient temperature

5: 79 percent / HCl / H₂O / 20 h / Heating

With pyridine; hydrogenchloride; sodium azide; ammonia; hydrogen; ammonium bromide; platinum(IV) oxide; In methanol; water;

Reference yield:

methylester of 3-benzyloxycyclobutane-1-carboxylic acid (4934-98-9) → hydrochloride of cis-3-aminocyclobutane-1-carboxylic acid (84182-59-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 85 percent / H₂ / PtO₂ / methanol / 7 h

2: 88 percent / pyridine / 336 h

3: 80 percent / NH₄Br, NH₃ / 144 h / Ambient temperature

4: 59 percent / NaN₃ / methanol; H₂O / 20 h / Heating

5: 81 percent / H₂ / PtO₂ / methanol / 6 h / Ambient temperature

6: 79 percent / HCl / H₂O / 20 h / Heating

With pyridine; hydrogenchloride; sodium azide; ammonia; hydrogen; ammonium bromide; platinum(IV) oxide; In methanol; water;

upstream raw materials:

hydrochloride of amide of cis-3-aminocyclobutane-1-carboxylic acid

methylester of 3-hydroxycyclobutane-1-carboxylic acid

methylester of 3-benzyloxycyclobutane-1-carboxylic acid

3-(benzyloxy)cyclobutane-1,1-dicarboxylic acid

Refernces