2-(2-Methylbut-3-en-2-yl)phenol

Base Information

• Chemical Name: 2-(2-Methylbut-3-en-2-yl)phenol
• CAS No.: 18272-61-2
• Molecular Formula: C11H14O
• Molecular Weight: 162.232
• NSC Number: 203035
• DSSTox Substance ID: DTXSID00308311
• Wikidata: Q82056116
• Mol file: 18272-61-2.mol

Synonyms:18272-61-2;2-(2-methylbut-3-en-2-yl)phenol;NSC203035;SCHEMBL1135764;DTXSID00308311;NSC-203035

Chemical Property of 2-(2-Methylbut-3-en-2-yl)phenol

Chemical Property:

• Vapor Pressure: 0.0369mmHg at 25°C
• Boiling Point: 233.3°Cat760mmHg
• Flash Point: 104.7°C
• Density: 0.976g/cm³
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 162.104465066
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C=C)C1=CC=CC=C1O

Technology Process of 2-(2-Methylbut-3-en-2-yl)phenol

There total 6 articles about 2-(2-Methylbut-3-en-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

3-methyl-2-buten-1-ol (556-82-1) + phenol (108-95-2,27073-41-2) → 4-(3-methylbut-2-en-1-yl)phenol (1200-09-5) + 4-(2-methylbut-3-en-2-yl)phenol (18272-68-9) + α,α-dimethyl-2-allylphenol (18272-61-2) + 2-prenylphenol (1128-92-3) + 2,6-bis-(3-methyl-2-butenyl)phenol (56850-70-5) + 2,6-bis(2-methylbut-3-en-2-yl)phenol

Guidance literature:

phenol; With aluminium; at 40 - 160 ℃;

3-methyl-2-buten-1-ol; at 160 ℃; for 3h;

DOI:10.1007/s10600-018-2245-y

Reference yield: 45.0%

2-(1',1'-dimethylprop-2'-enyl)phenyl acetate (59671-72-6) → α,α-dimethyl-2-allylphenol (18272-61-2)

Guidance literature:

With lithium aluminium tetrahydride;

Reference yield:

phenyl prenyl ether (14309-15-0) → α,α-dimethyl-2-allylphenol (18272-61-2)

Guidance literature:

With sodium carbonate;

DOI:10.1021/ja01526a021

upstream raw materials:

phenyl prenyl ether

2-(1',1'-dimethylprop-2'-enyl)phenyl acetate

Methylenetriphenylphosphorane

sodium phenoxide

Downstream raw materials:

4-(2'-hydroxyphenyl)-4-methylpentanal

5,5-dimethyl-2,3,4,5-tetrahydro-1-benzoxepin-2-ol