Benzamide,5-bromo-N-[[(2R)-1-[(4-fluorophenyl)methyl]-2-pyrrolidinyl]methyl]-2,3-dimethoxy-

Base Information

Chemical Name:Benzamide,5-bromo-N-[[(2R)-1-[(4-fluorophenyl)methyl]-2-pyrrolidinyl]methyl]-2,3-dimethoxy-
CAS No.:107188-82-9
Molecular Formula:C₂₁H₂₄BrFN₂O₃
Molecular Weight:451.336
Hs Code.:

Synonyms:Benzamide,5-bromo-N-[[1-[(4-fluorophenyl)methyl]-2-pyrrolidinyl]methyl]-2,3-dimethoxy-,(R)-; NCQ 115

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide,5-bromo-N-[[(2R)-1-[(4-fluorophenyl)methyl]-2-pyrrolidinyl]methyl]-2,3-dimethoxy-

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MSDS Files:: SDS file from LookChem

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Technology Process of Benzamide,5-bromo-N-[[(2R)-1-[(4-fluorophenyl)methyl]-2-pyrrolidinyl]methyl]-2,3-dimethoxy-

There total 2 articles about Benzamide,5-bromo-N-[[(2R)-1-[(4-fluorophenyl)methyl]-2-pyrrolidinyl]methyl]-2,3-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72517-23-8
5-bromo-2,3-dimethoxybenzoic acid

: 107188-82-9
5-Bromo-N-[(R)-1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2,3-dimethoxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride, DMF, / toluene / 3 h / 60 °C

2: CH₂Cl₂ / Ambient temperature

With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; toluene;
DOI:10.1021/jm00107a012