4-[2-(4-Methoxyphenyl)cyclopropyl]benzonitrile

Base Information

Chemical Name:4-[2-(4-Methoxyphenyl)cyclopropyl]benzonitrile
CAS No.:74261-28-2
Molecular Formula:C₁₇H₁₅NO
Molecular Weight:249.312
Hs Code.:
NSC Number:86476
DSSTox Substance ID:DTXSID60292924

Synonyms:74261-28-2;4-[2-(4-methoxyphenyl)cyclopropyl]benzonitrile;NSC86476;DTXSID60292924;NSC-86476

Suppliers and Price of 4-[2-(4-Methoxyphenyl)cyclopropyl]benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-[2-(4-Methoxyphenyl)cyclopropyl]benzonitrile

Chemical Property:

Vapor Pressure:1.82E-06mmHg at 25°C
Boiling Point:395.6°Cat760mmHg
Flash Point:166.4°C
Density:1.16g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:249.115364102
Heavy Atom Count:19
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2CC2C3=CC=C(C=C3)C#N

Technology Process of 4-[2-(4-Methoxyphenyl)cyclopropyl]benzonitrile

There total 5 articles about 4-[2-(4-Methoxyphenyl)cyclopropyl]benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 544-92-3
copper(I) cyanide

: 77153-50-5,77153-51-6
1-(p-chlorophenyl)-2-(p-methoxyphenyl)cyclopropane

: 77153-57-2,74261-28-2
(trans)-1-(p-Cyanophenyl)-2-(p-methoxyphenyl)cyclopropane

Guidance literature:: With 1-methyl-pyrrolidin-2-one; for 65h; Heating;
DOI:10.1021/jo00325a014

Reference yield:

: 637-69-4,24936-44-5
4-Methoxystyrene

: 41780-79-4
N'-(4-cyanobenzylidene)-4-methylbenzenesulfonohydrazide

: 74261-28-2
4-(2-(4-methoxyphenyl)cyclopropyl)benzonitrile

Guidance literature:: With potassium carbonate; In 1,4-dioxane; at 110 ℃; for 6h; Inert atmosphere; Schlenk technique;
DOI:10.1021/jacs.1c12071

Reference yield:

: 105-07-7
4-cyanobenzaldehyde

: 74261-28-2
4-(2-(4-methoxyphenyl)cyclopropyl)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / H₂O / Ambient temperature

2: 1.) hydrazine, 2.) KOH / 1.) diethylene glycol, 190 deg C, 1.5 h, 2.) 200 deg C, 3 h

With potassium hydroxide; sodium hydroxide; hydrazine; In water;
DOI:10.1080/00268948008071428