Hexitol,1,4-anhydro-, 6-dodecanoate

Base Information

• Chemical Name: Hexitol,1,4-anhydro-, 6-dodecanoate
• CAS No.: 16287-68-6
• Molecular Formula: C₁₈H₃₄O₆
• Molecular Weight: 346.464
• Mol file: 16287-68-6.mol

Synonyms:NSC406169

Chemical Property of Hexitol,1,4-anhydro-, 6-dodecanoate

Chemical Property:

• Boiling Point: 516.1°Cat760mmHg
• Flash Point: 176.9°C
• Density: 1.123g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Hexitol,1,4-anhydro-, 6-dodecanoate

There total 3 articles about Hexitol,1,4-anhydro-, 6-dodecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

lauric acid (143-07-7) + 1,4-anhydro-D-glucitol (7726-97-8,10334-28-8,20662-31-1,22554-76-3,22554-77-4,22554-79-6,27299-12-3,28218-56-6,32742-35-1,40026-08-2,51196-40-8,51607-77-3,53648-56-9,96243-58-2,124379-08-4,124379-13-1) → Span 20 (120200-78-4,16287-68-6,5959-89-7)

Guidance literature:

With lipase; In hexane; tert-butyl alcohol; at 64 ℃; Enzymatic reaction;

DOI:10.1039/c5gc02131f

Reference yield:

D-sorbitol (50-70-4) → Span 20 (120200-78-4,16287-68-6,5959-89-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; water / 74 h / 104 °C

2: lipase / tert-butyl alcohol; hexane / 64 °C / Enzymatic reaction

With sulfuric acid; water; lipase; In hexane; tert-butyl alcohol;

DOI:10.1039/c5gc02131f

Reference yield:

→ Span 20 (120200-78-4,16287-68-6,5959-89-7)

Guidance literature:

upstream raw materials:

lauric acid

1,4-anhydro-D-glucitol

D-sorbitol

Downstream raw materials:

N-((1S,2R)-2-hydroxy-1-hydroxymethyl-heptadecyl)-lauramide

Refernces

• 1、 -. "PRECIPITATION POLYMERIZATION IN THE PRESENCE OF GLYCERIN MONOSTEARATE". . . Retrieved 2011/06/28.
• 2、 -. "Phospholipid-and cholestrol-free aqueous composition for topical application to the skin". . . Retrieved 2008/06/13.