4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine

Base Information

• Chemical Name: 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine
• CAS No.: 52722-86-8
• Deprecated CAS: 116543-66-9,117247-95-7,1071912-36-1,1071912-36-1,117247-95-7
• Molecular Formula: C11H23NO2
• Molecular Weight: 201.309
• Hs Code.: 2933399090
• European Community (EC) Number: 258-132-1
• UNII: 800861N5IX
• DSSTox Substance ID: DTXSID4068795
• Nikkaji Number: J31.379C
• Wikidata: Q27269089
• Mol file: 52722-86-8.mol

Synonyms:52722-86-8;1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidin-4-ol;4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine;1-(2-Hydroxyethyl)-2,2,6,6-tetramethyl-4-piperidinol;1-Piperidineethanol, 4-hydroxy-2,2,6,6-tetramethyl-;4-Hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol;EINECS 258-132-1;1-(2-hydroxyethyl)-2,2,6,6-tetramethyl-4-hydroxypiperidine;4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol;1-(2'-Hydroxyethyl)-2,2,6,6-tetramethyl-4-piperidinol;UNII-800861N5IX;1-(2-Hydroxyethyl)-4-hydroxy-2,2,6,6-tetramethylpiperidine;800861N5IX;EC 258-132-1;SCHEMBL39066;DTXSID4068795;1-(2i-Hydroxyethyl)-2,2,6,6-Tetramethyl-4-Piperidinol;CHEBI:182655;N-(2'-Hydroxyethyl)-4-hydroxy-2,2,6,6-tetramethylpiperidine;CCA72286;MFCD01321174;STK693437;AKOS005604964;CS-W015549;SB43284;AS-68993;FT-0640100;FT-0690732;H0931;D81950;2,2,6,6-Tetramethyl-4-hydroxy-1-piperidineethanol;W-105803;1-Ethanol, 4-hydroxy-2,2,6,6-tetramethylpiperidine-;4-hydroxy-2,2,6,6-tetramethyl-1-piperidine ethanol;Q27269089;N-(2-hydroxyethyl)-2,2,6,6,-tetramethyl-4-piperidinol;1-(2'Hydroxyethyl)-2,2,6,6- tetramethyl-4-piperidinol;4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6tetramethylpiperidine;N-2-HYDROXYETHYL-4-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDINE

Chemical Property of 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine

Chemical Property:

• Appearance/Colour: white crystal powder
• Vapor Pressure: 9.49E-05mmHg at 25°C
• Melting Point: 180-184 °C
• Refractive Index: 1.471
• Boiling Point: 302.6 °C at 760 mmHg
• PKA: 14.89±0.60(Predicted)
• Flash Point: 130.2 °C
• PSA: 43.70000
• Density: 0.975 g/cm³
• LogP: 0.93050
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: 28g/L at 20℃
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 201.172878976
• Heavy Atom Count: 14
• Complexity: 184

Purity/Quality:

99.9% ^*data from raw suppliers

4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC(CC(N1CCO)(C)C)O)C
• Uses: Light stabilizer 201 is a important intermediate of hindered amine light stability agent and synthetic hindered amine light stability agent. Also as a important intermediate of the medicine and epoxy resin crosslinking.

Technology Process of 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine

There total 3 articles about 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxirane (75-21-8,99932-75-9) + 4-hydroxy-2,2,6,6-tetramethylpiperidine (2403-88-5) → N-(2-hydroxyethyl)-2,2,6,6-tetramethyl-4piperidinol (52722-86-8)

Guidance literature:

In isopropyl alcohol; toluene;

Reference yield:

→ N-(2-hydroxyethyl)-2,2,6,6-tetramethyl-4piperidinol (52722-86-8)

Guidance literature:

entspr. N-unsubst. Piperidin-4-ol, Ethylenoxid;

Reference yield:

→ N-(2-hydroxyethyl)-2,2,6,6-tetramethyl-4piperidinol (52722-86-8) + 2,4-di-tert-butyl-6-methylphenylphosphorodichloridite (158012-38-5)

Guidance literature:

upstream raw materials:

oxirane

4-hydroxy-2,2,6,6-tetramethylpiperidine

Downstream raw materials:

1-[2-[3-(3,5-di-tert-butyl-4-hydroxy-phenyl)propionyloxy]-ethyl]-4-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)-propionyloxy]-2,2,6,6-tetramethyl-piperidine

Refernces

• 1、 -. "Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same". . . Retrieved 2008/06/13.
• 2、 -. "Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same". . . Retrieved 2008/06/13.