9H-fluorene-3-carboxylic Acid

Base Information

• Chemical Name: 9H-fluorene-3-carboxylic Acid
• CAS No.: 92151-76-3
• Molecular Formula: C14H10 O2
• Molecular Weight: 210.232
• Hs Code.: 2916399090
• European Community (EC) Number: 868-839-2
• DSSTox Substance ID: DTXSID10427946
• Wikidata: Q82240698
• Mol file: 92151-76-3.mol

Synonyms:9H-fluorene-3-carboxylic Acid;92151-76-3;3-Fluorenecarboxylic Acid;Fluoren-3-ylcarboxylic acid;SCHEMBL3105349;DTXSID10427946;WYRSPZVTTMUNBL-UHFFFAOYSA-N;HMS1730B04;STL164075;AKOS000119243;CS-0239735;EN300-21828;AB00745005-01;A916341;Z119984124

Chemical Property of 9H-fluorene-3-carboxylic Acid

Chemical Property:

• Vapor Pressure: 2.02E-07mmHg at 25°C
• Boiling Point: 408.9°Cat760mmHg
• Flash Point: 183.9°C
• PSA: 37.30000
• Density: g/cm³
• LogP: 2.95600
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 210.068079557
• Heavy Atom Count: 16
• Complexity: 287

Purity/Quality:

98%Min ^*data from raw suppliers

9H-FLUORENE-3-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2=C(C=C(C=C2)C(=O)O)C3=CC=CC=C31

Technology Process of 9H-fluorene-3-carboxylic Acid

There total 10 articles about 9H-fluorene-3-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-oxo-9H-fluorene-3-carboxylic acid (38570-92-2) → Fluorene-3-carboxylic acid (92151-76-3)

Guidance literature:

With hydrogenchloride; amalgamated zinc;

DOI:10.1039/jr9520000299

Reference yield:

2,5-dimethylphenylmagnesium bromide (30897-86-0) → Fluorene-3-carboxylic acid (92151-76-3)

Guidance literature:

Multi-step reaction with 6 steps

2: aqueous HCl; acetic acid

3: chloranil; xylene

4: KMnO₄

5: polyphosphoric acid

6: N₂H₄+H₂O; NaOH

With hydrogenchloride; sodium hydroxide; potassium permanganate; PPA; chloranil; hydrazine hydrate; acetic acid; xylene;

DOI:10.1021/jo01102a029

Reference yield:

methyl 9-oxo-9H-fluorene-3-carboxylate (19063-40-2) → Fluorene-3-carboxylic acid (92151-76-3)

Guidance literature:

With phosphorus; hydrogen iodide; acetic acid;

DOI:10.1021/jo01103a602

upstream raw materials:

9-oxo-9H-fluorene-3-carboxylic acid

methyl 9-oxo-9H-fluorene-3-carboxylate

2,5-biphenyldicarboxylic acid

2,5-dimethylbiphenyl

Downstream raw materials:

methyl fluorene-3-carboxylate

2-Amino-7-nitro-fluoren

Refernces

• 1、 -. "Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same". Page/Page column 8. . Retrieved 2010/02/10.