N-iodoacetyltyramine

Base Information

• Chemical Name: N-iodoacetyltyramine
• CAS No.: 53527-07-4
• Molecular Formula: C10H12 I N O2
• Molecular Weight: 305.115
• Mol file: 53527-07-4.mol

Synonyms:N-Iodoacetyltyramine

Chemical Property of N-iodoacetyltyramine

Chemical Property:

• Vapor Pressure: 5.69E-10mmHg at 25°C
• Boiling Point: 483.5°Cat760mmHg
• PKA: 10.00±0.15(Predicted)
• Flash Point: 246.2°C
• PSA: 49.33000
• Density: 1.709g/cm³
• LogP: 1.87680
• Storage Temp.: Refrigerator
• Solubility.: Acetone (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

N-Iodoacetyltyramine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Iodoacetyltyramine is used in iodine-125 labelling of various molecules for chemical analysis.

Technology Process of N-iodoacetyltyramine

There total 1 articles about N-iodoacetyltyramine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ β-(4-hydroxyphenyl)ethyl iodoacetamide (53527-07-4)

Guidance literature:

entspr. Chloracetylamin, KI, wfr. Acn., Δ;

Reference yield: 94.0%

β-(4-hydroxyphenyl)ethyl iodoacetamide (53527-07-4) + 2-(((3-acetamido-4-methoxy-2-methyl-4-oxobutan-2-yl)disulfanecarbonyl)(methyl)amino)ethan-1-aminium trifluoroacetate → 1-methyl-2-imidazolidone (694-32-6) + methyl 2-acetamido-3-((2-((4-hydroxyphenethyl)amino)-2-oxoethyl)disulfaneyl)-3-methylbutanoate

Guidance literature:

With diethylenetriaminopentaacetic acid; In aq. buffer; at 37 ℃; for 2h; pH=7.4; Solvent; pH-value; Kinetics;

DOI:10.1021/jacs.9b12180

Reference yield: 90.0%

β-(4-hydroxyphenyl)ethyl iodoacetamide (53527-07-4) + 3-(((3-acetamido-4-methoxy-2-methyl-4-oxobutan-2-yl)disulfanecarbonyl)(methyl)amino)-N-methylpropan-1-aminium trifluoroacetate → 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (7226-23-5) + β-(4-hydroxyphenyl)ethyl-2-aminoacetamide (55710-99-1) + methyl 2-acetamido-3-((2-((4-hydroxyphenethyl)amino)-2-oxoethyl)disulfaneyl)-3-methylbutanoate + C18H26N2O5S

Guidance literature:

With diethylenetriaminopentaacetic acid; In aq. buffer; at 37 ℃; for 7h; pH=7.4; Solvent; pH-value; Kinetics;

DOI:10.1021/jacs.9b12180

Downstream raw materials:

1,3-dimethyl-2-imidazolidinone

1-methyl-2-imidazolidone

1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

β-(4-hydroxyphenyl)ethyl-2-aminoacetamide