ethyl (E)-3-[[2-amino-6-(ethoxycarbonylamino)pyridin-3-yl]amino]-3-phenylprop-2-enoate

Base Information

Chemical Name:ethyl (E)-3-[[2-amino-6-(ethoxycarbonylamino)pyridin-3-yl]amino]-3-phenylprop-2-enoate
CAS No.:83269-29-8
Molecular Formula:C19H22N4O4
Molecular Weight:370.4024
Hs Code.:
NSC Number:330771
ChEMBL ID:CHEMBL435671

Synonyms:NSC330771;CHEMBL435671;83269-29-8;NSC-330771

Suppliers and Price of ethyl (E)-3-[[2-amino-6-(ethoxycarbonylamino)pyridin-3-yl]amino]-3-phenylprop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of ethyl (E)-3-[[2-amino-6-(ethoxycarbonylamino)pyridin-3-yl]amino]-3-phenylprop-2-enoate

Chemical Property:

Vapor Pressure:5.29E-11mmHg at 25°C
Boiling Point:522.2°Cat760mmHg
Flash Point:269.6°C
Density:1.297g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:370.16410520
Heavy Atom Count:27
Complexity:520

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=C(C1=CC=CC=C1)NC2=C(N=C(C=C2)NC(=O)OCC)N
Isomeric SMILES:CCOC(=O)/C=C(\C1=CC=CC=C1)/NC2=C(N=C(C=C2)NC(=O)OCC)N

Technology Process of ethyl (E)-3-[[2-amino-6-(ethoxycarbonylamino)pyridin-3-yl]amino]-3-phenylprop-2-enoate

There total 2 articles about ethyl (E)-3-[[2-amino-6-(ethoxycarbonylamino)pyridin-3-yl]amino]-3-phenylprop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 83269-29-8
ethyl 6-amino-5-<<1-(ethoxycarbonyl)-2-phenylethen-2-yl>amino>-2-pyridinecarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / ethanol / 8 h / 760 Torr / Ambient temperature

2: Et₃N / ethanol / 103 h / Heating

With hydrogen; triethylamine; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00355a018