Levetimide

Base Information

Chemical Name:Levetimide
CAS No.:21888-99-3
Molecular Formula:C23H26 N2 O2
Molecular Weight:362.472
Hs Code.:
UNII:576087I4XG
DSSTox Substance ID:DTXSID401183493
Nikkaji Number:J83.109C
Wikidata:Q27080260
Pharos Ligand ID:QFF44TG88132
Mol file:21888-99-3.mol

Synonyms:levetimide

Suppliers and Price of Levetimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Levetimide

Chemical Property:

Boiling Point:543.9°Cat760mmHg
Flash Point:282.7°C
Density:1.178g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:362.199428076
Heavy Atom Count:27
Complexity:529

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
Isomeric SMILES:C1CN(CCC1[C@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4

Technology Process of Levetimide

There total 1 articles about Levetimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14051-33-3
Benzetimide

: 21888-98-2
[125I]-Dexetimide

: 21888-99-3
Levetimide

Guidance literature:: In ethanol; n-heptane; Purification / work up; Resolution of racemate;

Reference yield: 93.3%

: 21888-99-3
Levetimide

: 115216-88-1
(R)-(-)-3-Phenyl-3-(4-piperidinyl)-2,6-piperidinedione

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol;

Reference yield:

: 21888-99-3
Levetimide

: 119391-68-3
(R)-3-Phenyl-3-<1-<<4-(trimethylsilyl)phenyl>methyl>-4-piperidinyl>-2,6-piperidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, conc. aq. HCl / 5percent Pd/C / methanol / 72 h / 3102.9 Torr / Ambient temperature

2: 1) Na₂CO₃, 2) aq. HCl / 1) EtOH, reflux, 0.5 h

With hydrogenchloride; hydrogen; sodium carbonate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00125a021