Propanal, 3-hydroxy-2,2-bis(hydroxymethyl)-

Base Information

• Chemical Name: Propanal, 3-hydroxy-2,2-bis(hydroxymethyl)-
• CAS No.: 3818-32-4
• Molecular Formula: C5H10O4
• Molecular Weight: 134.132
• Hs Code.: 2912491000
• European Community (EC) Number: 223-305-2
• DSSTox Substance ID: DTXSID3063201
• Nikkaji Number: J60.732K
• Wikidata: Q81990561
• Mol file: 3818-32-4.mol

Synonyms:3818-32-4;Propanal, 3-hydroxy-2,2-bis(hydroxymethyl)-;3-hydroxy-2,2-bis(hydroxymethyl)propanal;EINECS 223-305-2;3-Hydroxy-2,2-bis(hydroxymethyl)propionaldehyde;Pentaerythrose;trimethylolacetaldehyde;SCHEMBL771717;tris(hydroxymethyl)acetaldehyde;DTXSID3063201;3-OH-2,2-bis(OHmethyl)propionaldehyde;W-109932

Chemical Property of Propanal, 3-hydroxy-2,2-bis(hydroxymethyl)-

Chemical Property:

• Vapor Pressure: 2.53E-07mmHg at 25°C
• Refractive Index: 1.505
• Boiling Point: 379.683 °C at 760 mmHg
• Flash Point: 197.601 °C
• PSA: 77.76000
• Density: 1.329 g/cm³
• LogP: -1.85140
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 134.05790880
• Heavy Atom Count: 9
• Complexity: 78.7

Purity/Quality:

99% ^*data from raw suppliers

3-HYDROXY-2,2-BIS(HYDROXYMETHYL)PROPANAL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(CO)(CO)C=O)O

Technology Process of Propanal, 3-hydroxy-2,2-bis(hydroxymethyl)-

There total 5 articles about Propanal, 3-hydroxy-2,2-bis(hydroxymethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + acetaldehyde (75-07-0,9002-91-9) → tri(hydroxymethyl)acetaldehyde (3818-32-4)

Guidance literature:

With sodium hydroxide; water;

DOI:10.1016/0009-2509(59)80025-7

Reference yield:

dimethoxymethyl-hydroxymethyl-malonic acid dimethyl ester (40364-87-2) → tri(hydroxymethyl)acetaldehyde (3818-32-4)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: aq. H₂SO₄

With lithium aluminium tetrahydride; sulfuric acid; In diethyl ether;

Reference yield:

2-dimethoxymethyl-2-hydroxymethyl-propane-1,3-diol (40364-88-3) → tri(hydroxymethyl)acetaldehyde (3818-32-4)

Guidance literature:

With sulfuric acid;

upstream raw materials:

formaldehyd

acetaldehyde

2-dimethoxymethyl-2-hydroxymethyl-propane-1,3-diol

dimethoxymethyl-hydroxymethyl-malonic acid dimethyl ester

Downstream raw materials:

Pentaerythritol