(5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid

Base Information

Chemical Name:(5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid
CAS No.:7510-15-8
Molecular Formula:C₁₂H₁₃NO₃
Molecular Weight:219.24
Hs Code.:
NSC Number:405601
DSSTox Substance ID:DTXSID60324057
Nikkaji Number:J885.359B
Wikidata:Q82083443

Synonyms:7510-15-8;(5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid;NSC 405601;2-(5-methoxy-1-methylindol-3-yl)acetic acid;NSC405601;2-(5-methoxy-1-methyl-1H-indol-3-yl)acetic acid;SCHEMBL2685182;DTXSID60324057;NSC-405601;1-Methyl-5-methoxy-1H-indole-3-acetic acid

Suppliers and Price of (5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid

Chemical Property:

Vapor Pressure:5.05E-08mmHg at 25°C
Boiling Point:426.2°Cat760mmHg
Flash Point:211.5°C
Density:1.22g/cm³
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:219.08954328
Heavy Atom Count:16
Complexity:269

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=C(C2=C1C=CC(=C2)OC)CC(=O)O

Technology Process of (5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid

There total 5 articles about (5-Methoxy-1-methyl-1H-indol-3-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: methyl 2-(5-methoxy-1-methyl-1H-indol-3-yl)acetate

: 7510-15-8
2-(5-methoxy-1-methyl-1H-indol-3-yl)acetic acid

Guidance literature:

Reference yield:

: 3471-31-6,142396-09-6
5-methoxy-1H-indole-3-acetic acid

: 7510-15-8
2-(5-methoxy-1-methyl-1H-indol-3-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: sodium hydroxide / methanol / 3 h / Reflux; Inert atmosphere

With sodium hydride; sodium hydroxide; In methanol; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201103151