5-Methoxy-1H-indole-3-acetic acid methyl ester

Base Information

• Chemical Name: 5-Methoxy-1H-indole-3-acetic acid methyl ester
• CAS No.: 23304-48-5
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Hs Code.: 2933990090
• Mol file: 23304-48-5.mol

Synonyms:Indole-3-acetic acid,5-methoxy-,methyl ester;5-methoxy-3-indolylacetic acid methyl ester;1H-Indole-3-acetic acid,5-methoxy-,methyl ester;Methyl ester of 5-methoxyindoleacetic acid;5-methoxyindole-3-acetic acid methyl ester;

Chemical Property of 5-Methoxy-1H-indole-3-acetic acid methyl ester

Chemical Property:

• PSA: 51.32000
• LogP: 1.89200

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-(5-methoxy-1H-indol-3-yl)acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Methoxy-1H-indole-3-acetic acid methyl ester

There total 13 articles about 5-Methoxy-1H-indole-3-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-methoxy-1H-indole-3-acetic acid (3471-31-6,142396-09-6) + methyl iodide (74-88-4) → (5-methoxy-1H-indol-3-yl)acetic acid methyl ester (23304-48-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

Reference yield: 94.0%

methyl 2-(5-methoxy-1H-indol-3-yl)-2-oxoacetate (99988-56-4) → (5-methoxy-1H-indol-3-yl)acetic acid methyl ester (23304-48-5)

Guidance literature:

With sodium hypophosphite; isobutyric Acid; palladium on activated charcoal; In 1,4-dioxane; water; at 20 ℃; for 48h;

DOI:10.1016/j.phytochem.2007.04.030

Reference yield: 92.0%

methanol (67-56-1) + 5-methoxy-1H-indole-3-acetic acid (3471-31-6,142396-09-6) → (5-methoxy-1H-indol-3-yl)acetic acid methyl ester (23304-48-5)

Guidance literature:

With sulfuric acid; for 2h; Heating;

DOI:10.1002/(SICI)1099-1344(199708)39:8<677::AID-JLCR9>3.0.CO;2-G

upstream raw materials:

methanol

5-methoxy-1H-indole-3-acetic acid

methyl 2-(5-methoxy-1H-indol-3-yl)-2-oxoacetate

5-methoxylindole

Downstream raw materials:

5-methoxytryptophol

5-methoxy-1H-indole-3-acetic acid

C₂₄H₂₈O₄N₂

bufotenin