3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one

Base Information

Chemical Name:3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one
CAS No.:76299-53-1
Molecular Formula:C₁₂H₁₂O₅S
Molecular Weight:268.29
Hs Code.:
NSC Number:178878
DSSTox Substance ID:DTXSID20419413
Nikkaji Number:J640.627K
Wikidata:Q82230403
ChEMBL ID:CHEMBL3274513

Synonyms:NSC178878;76299-53-1;CHEMBL3274513;DTXSID20419413;NSC-178878;3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one

Suppliers and Price of 3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one

Chemical Property:

Vapor Pressure:4.08E-09mmHg at 25°C
Boiling Point:473°C at 760 mmHg
Flash Point:239.9°C
Density:1.444g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:268.04054465
Heavy Atom Count:18
Complexity:438

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OC=C2CCOC2=O
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)O/C=C/2\CCOC2=O

Technology Process of 3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one

There total 1 articles about 3-[(E)-Tosyloxymethylene]tetrahydrofuran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 547-65-9
α-methylene-γ-butyrolactone

: 98-59-9
p-toluenesulfonyl chloride

: 76299-53-1
3-(toluene-4-sulfonyloxymethylene)-dihydro-furan-2-one

Guidance literature:: With sodium hydride; Multistep reaction; 1.) HCOOEt;
DOI:10.1021/jo00319a020

Reference yield:

: 34907-24-9
N-(p-Nitrobenzyl) benzamide

: 76299-53-1
3-(toluene-4-sulfonyloxymethylene)-dihydro-furan-2-one

: C₁₉H₁₅NO₂

Guidance literature:: N-(p-Nitrobenzyl) benzamide; With thionyl chloride; at 45 - 50 ℃;

3-(toluene-4-sulfonyloxymethylene)-dihydro-furan-2-one; With potassium tert-butylate; In tetrahydrofuran; Further stages.;
DOI:10.1021/jo702563n