Chemical Property of alpha-Methylene-gamma-butyrolactone
Chemical Property:
- Appearance/Colour:clear colourless to light yellow or slightly pink
- Vapor Pressure:0.264mmHg at 25°C
- Melting Point:<25 °C
- Refractive Index:n20/D 1.472(lit.)
- Boiling Point:204.4 °C at 760 mmHg
- Flash Point:83.6 °C
- PSA：26.30000
- Density:1.07 g/cm3
- LogP:0.48950
- Storage Temp.:2-8°C
- Solubility.:water: soluble(lit.)
- XLogP3:0.8
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:0
- Exact Mass:98.036779430
- Heavy Atom Count:7
- Complexity:115
- Purity/Quality:
-
99% *data from raw suppliers
α-Methylene-γ-butyrolactone *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
42/43-52/53-10
- Safety Statements:
23-36/37-61-45
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C=C1CCOC1=O
-
Description
Tulipalin A is an unsubstituted -methylene-butyrolaetone
eontained in the sap of tulips, Alstroemeria spp.
(Peruvian lily) and Erythronium (dog tooth violet,
fawn-lily). Tulipalin B seems to have a weak capacities
to sensitize.
-
Uses
Very reactive Michael-acceptor; the α-methylene-γ-butyrolactone ring system exists in many natural products of biological interest Allergen in the Liliaeeae family of plants to whieh speeies such as Tulip, Alstromeria, Erythronium dens canis and americanum belong. α-Methylene-γ-butyrolactone (Tulipane) was used to develop optically active spiro-[butyrolactone-pyrrolidine] via Cu(I)-catalyzed exo-selective 1,3-dipolar cycloaddition of azomethine ylides.
