2-(4-chlorophenyl)-3-oxo-3-phenylpropanenitrile

Base Information

• Chemical Name: 2-(4-chlorophenyl)-3-oxo-3-phenylpropanenitrile
• CAS No.: 5415-05-4
• Molecular Formula: C15H10 Cl N O
• Molecular Weight: 255.703
• Mol file: 5415-05-4.mol

Synonyms:Acetonitrile,benzoyl(p-chlorophenyl)- (6CI,8CI); 2-(4-Chlorophenyl)-2-cyanoacetophenone; NSC11187

Chemical Property of 2-(4-chlorophenyl)-3-oxo-3-phenylpropanenitrile

Chemical Property:

• Vapor Pressure: 4.5E-07mmHg at 25°C
• Boiling Point: 414.3°Cat760mmHg
• Flash Point: 204.3°C
• Density: 1.251g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-chlorophenyl)-3-oxo-3-phenylpropanenitrile

There total 3 articles about 2-(4-chlorophenyl)-3-oxo-3-phenylpropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-chlorobenzyl cyanide (140-53-4) → 2-(4-chloro-phenyl)-3-oxo-3-phenyl-propionitrile (5415-05-4)

Guidance literature:

With sodium ethanolate;

Reference yield:

benzoyl cyanide (613-90-1) + p-chlorobenzyl cyanide (140-53-4) → 2-(4-chloro-phenyl)-3-oxo-3-phenyl-propionitrile (5415-05-4)

Guidance literature:

With triethylamine;

DOI:10.1007/BF03166126

Reference yield:

→ 2-(4-chloro-phenyl)-3-oxo-3-phenyl-propionitrile (5415-05-4)

Guidance literature:

p-Chlorphenylacetonitril, Ethylbenzoat;

DOI:10.1021/jo00832a024

upstream raw materials:

benzoyl cyanide

p-chlorobenzyl cyanide

Downstream raw materials:

benzoic acid

p-chlorobenzyl cyanide

2-(4-chloro-phenyl)-3-oxo-3-phenyl-propionic acid amide

2-(4-chlorophenyl)-1-phenylethanone