L-Cycloserine

Base Information Edit

Chemical Name:L-Cycloserine
CAS No.:339-72-0
Deprecated CAS:433-56-7
Molecular Formula:C3H6N2O2
Molecular Weight:102.093
Hs Code.:2934999090
European Community (EC) Number:206-427-0
UNII:AK7DRB7FMO
DSSTox Substance ID:DTXSID701017231
Nikkaji Number:J71.275B
Wikidata:Q27145415
NCI Thesaurus Code:C81113
ChEMBL ID:CHEMBL448864
Mol file:339-72-0.mol

Synonyms:L-Cycloserine;339-72-0;Levcycloserine;(S)-4-Aminoisoxazolidin-3-one;Levcicloserina;Levcycloserinum;(4S)-4-amino-1,2-oxazolidin-3-one;Cyclo-L-serine;(S)-4-Amino-3-isoxazolidone;(S)-4-Amino-3-isoxazolidinone;(S)-(-)-Cycloserine;L-Oxamicina;Cycloserine, l-;(-)-cycloserine;L-4-Aminoisoxazolidin-3-one;L-Oxamicina [Italian];AK7DRB7FMO;UNII-AK7DRB7FMO;L-4-Amino-3-isoxazolidinone;Levcycloserine [USAN:INN];Levcycloserinum [INN-Latin];Levcicloserina [INN-Spanish];(-)-4-Amino-3-isossazolidone;CHEBI:75592;4-azaniumyl-4,5-dihydro-1,2-oxazol-3-olate;(4S)-4-aminoisoxazolidin-3-one;EINECS 206-427-0;3-Isoxazolidinone, 4-amino-, (S)-;NSC-760409;BRN 0080799;(-)-4-Amino-3-isossazolidone [Italian];4-27-00-05550 (Beilstein Handbook Reference);L-Cycloserin;(S)-Cycloserine;3-ISOXAZOLIDINONE, 4-AMINO-, (L)-;3-Isoxazolidinone, 4-amino-, (4S)-;L-CS;Prestwick0_001086;Prestwick1_001086;Prestwick2_001086;Prestwick3_001086;Levcycloserine (USAN/INN);LEVCYCLOSERINE [INN];Lopac0_000199;BSPBio_001132;LEVCYCLOSERINE [USAN];MLS000859981;SCHEMBL243772;SPBio_003026;BPBio1_001246;CHEMBL448864;GTPL9488;(-)-4-amino-3-isoxazolidinone;(-)-4-aminoisoxazolidin-3-one;(S)-4-amino-isoxazolidin-3-one;DTXSID701017231;HMS1571I14;HMS2098I14;HMS2235N07;HMS3260H19;HMS3264E06;HMS3715I20;(S)-3-Isoxazolidinone, 4-amino-;4AX;HY-B1122;Tox21_500199;BDBM50357231;FD3007;MFCD00064324;s3945;AKOS006237181;CCG-204294;CS-4717;LP00199;NSC 760409;SDCCGSBI-0050187.P002;NCGC00093674-01;NCGC00093674-02;NCGC00093674-03;NCGC00093674-04;NCGC00093674-07;NCGC00093674-08;NCGC00260884-01;DS-18395;SMR000326840;AB00514038;EU-0100199;C 1159;D04706;EN300-768780;AB00514038_05;SR-01000780566;J-502461;SR-01000780566-2;Q27145415;Z1201618622

Suppliers and Price of L-Cycloserine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-Cycloserine
5mg
$ 346.00

TRC
L-Cycloserine
10mg
$ 45.00

Sigma-Aldrich
L-Cycloserine
250mg
$ 322.00

Sigma-Aldrich
L-Cycloserine
25mg
$ 61.00

Sigma-Aldrich
L-Cycloserine
10mg
$ 47.20

Sigma-Aldrich
L-Cycloserine
100mg
$ 153.00

Crysdot
L-Cycloserine 97%
1g
$ 75.00

Crysdot
L-Cycloserine 97%
5g
$ 230.00

Crysdot
L-Cycloserine 97%
10g
$ 360.00

Crysdot
L-Cycloserine 97%
25g
$ 600.00

Total 79 raw suppliers

Chemical Property of L-Cycloserine Edit

Chemical Property:

Appearance/Colour:White powder
Melting Point:147 °C
Refractive Index:1.5110 (estimate)
Boiling Point:191.38°C (rough estimate)
PKA:14.36±0.40(Predicted)
PSA：64.35000
Density:1.278 g/cm³
LogP:-0.59580
Storage Temp.:2-8°C
Solubility.:H2O: soluble50mg/mg protein
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:102.042927438
Heavy Atom Count:7
Complexity:92.9

Purity/Quality:

99% ^*data from raw suppliers

L-Cycloserine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 5-20
Safety Statements: 38-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(=O)NO1)N
Isomeric SMILES:C1[C@@H](C(=O)NO1)N
Uses L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase.

Technology Process of L-Cycloserine

There total 16 articles about L-Cycloserine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1449601-12-0
C₃H₆N₂O₂*C₄H₆O₆

: 339-72-0
L-cycloserine

Guidance literature:: With Amberlite IR-120 PLUS ion exchange resin (sodium form); In water; Inert atmosphere;
DOI:10.3987/COM-12-12553

Reference yield: 51.0%

: 27010-92-0,114562-16-2
DL-β-aminoxyalanine methyl ester dihydrochloride

: 68-39-3,68-41-7,339-72-0,4834-58-6
4-amino-3-isoxazolidone

Guidance literature:: With potassium hydroxide; In methanol; water; at 0 - 20 ℃; for 1h; pH=11 - 11.5; Inert atmosphere;
DOI:10.3987/COM-12-12553