6-Methyl-1,4-dioxaspiro[4.5]decane

Base Information

• Chemical Name: 6-Methyl-1,4-dioxaspiro[4.5]decane
• CAS No.: 935-38-6
• Molecular Formula: C₉H₁₆O₂
• Molecular Weight: 156.225
• NSC Number: 157343
• DSSTox Substance ID: DTXSID20303207
• Nikkaji Number: J302.951D
• Mol file: 935-38-6.mol

Synonyms:6-methyl-1,4-dioxaspiro[4.5]decane;935-38-6;NSC157343;1,4-DIOXASPIRO[4.5]DECANE,6-METHYL-;SCHEMBL18576604;DTXSID20303207;6-methyl-1,4-dioxaspiro[4.5]decan;NSC-157343

Chemical Property of 6-Methyl-1,4-dioxaspiro[4.5]decane

Chemical Property:

• Vapor Pressure: 0.917mmHg at 25°C
• Boiling Point: 186.3°Cat760mmHg
• Flash Point: 63.8°C
• PSA: 18.46000
• Density: 1.01g/cm³
• LogP: 1.93960
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 156.115029749
• Heavy Atom Count: 11
• Complexity: 139

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCCCC12OCCO2

Technology Process of 6-Methyl-1,4-dioxaspiro[4.5]decane

There total 6 articles about 6-Methyl-1,4-dioxaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethylene glycol (107-21-1) + 2-Methylcyclohexanone (583-60-8) → 6-methyl-1,4-dioxa-spiro[4.5]decane (129917-45-9,935-38-6)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; Inert atmosphere; Reflux;

DOI:10.1002/anie.201002281

Reference yield: 90.0%

2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane (7381-30-8) + 2-Methylcyclohexanone (583-60-8) → 6-methyl-1,4-dioxa-spiro[4.5]decane (129917-45-9,935-38-6)

Guidance literature:

With lithium perchlorate; In dichloromethane; for 0.05h; Ambient temperature; electrolysis (platinum electrodes, 10 V, 0.4-0.5 mA);

DOI:10.1246/cl.1983.1349

Reference yield: 72.0%

(S)-6-Methyl-1,4-dioxa-spiro[4.5]dec-7-ene (132840-96-1) → (S)-6-Methyl-1,4-dioxa-spiro[4.5]decane (132883-11-5,935-38-6)

Guidance literature:

With hydrogen; platinum on activated charcoal; In methanol; for 3h; under 760 Torr;

DOI:10.1016/S0957-4166(00)80546-7

upstream raw materials:

ethylene glycol

2-Methylcyclohexanone

2-(Bicyclo[4.1.0]hept-1-yloxy)-ethanol

2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane