3-Fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine

Base Information

Chemical Name:3-Fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine
CAS No.:316-83-6
Molecular Formula:C₂₂H₂₇ClFN₃
Molecular Weight:387.928
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60953563
Mol file:316-83-6.mol

Synonyms:3-fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine;fluoroquinacrine

Suppliers and Price of 3-Fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine

Chemical Property:

Vapor Pressure:2.3E-11mmHg at 25°C
Boiling Point:531.1°Cat760mmHg
PKA:10.47±0.25(Predicted)
Flash Point:275°C
PSA：31.39000
Density:1.189g/cm³
LogP:5.52480
XLogP3:6.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:387.1877537
Heavy Atom Count:27
Complexity:447

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)F

Technology Process of 3-Fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine

There total 3 articles about 3-Fluoro-7-chloro-9-(diethylamino-1-methylbutylamino)acridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2367-04-6
5-chloro-4'-fluoro-diphenylamine-2-carboxylic acid

: 316-83-6
N⁴,N⁴-diethyl-N¹-(6-chloro-2-fluoro-acridin-9-yl)-1-methyl-butanediyldiamine

Guidance literature:: With trichlorophosphate; und Erwaermen des Reaktionsprodukts mit Phenol und 4-Amino-1-diaethylamino-pentan;
DOI:10.1021/ja01182a065

Reference yield:

: 50-84-0
2,4 dichlorobenzoic acid

: 316-83-6
N⁴,N⁴-diethyl-N¹-(6-chloro-2-fluoro-acridin-9-yl)-1-methyl-butanediyldiamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; potassium acetate; copper / weiteres Reagens: Butanol-⁽¹⁾

2: phosphoryl chloride / und Erwaermen des Reaktionsprodukts mit Phenol und 4-Amino-1-diaethylamino-pentan

With potassium acetate; copper; potassium carbonate; trichlorophosphate;
DOI:10.1021/ja01182a065

Reference yield:

: 371-40-4
4-fluoroaniline

: 316-83-6
N⁴,N⁴-diethyl-N¹-(6-chloro-2-fluoro-acridin-9-yl)-1-methyl-butanediyldiamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; potassium acetate; copper / weiteres Reagens: Butanol-⁽¹⁾

2: phosphoryl chloride / und Erwaermen des Reaktionsprodukts mit Phenol und 4-Amino-1-diaethylamino-pentan

With potassium acetate; copper; potassium carbonate; trichlorophosphate;
DOI:10.1021/ja01182a065