4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate

Base Information

Chemical Name:4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate
CAS No.:10512-93-3
Molecular Formula:C19H20 N2 O6
Molecular Weight:372.378
Hs Code.:2924299090
European Community (EC) Number:234-047-5
DSSTox Substance ID:DTXSID30146960
Nikkaji Number:J81.521G
Wikidata:Q83011864
ChEMBL ID:CHEMBL3278835
Mol file:10512-93-3.mol

Synonyms:Z-Val-ONp;10512-93-3;4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate;EINECS 234-047-5;(4-nitrophenyl) (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate;Z-L-Valine P-nitrophenyl ester;C19H20N2O6;(S)-4-NITROPHENYL 2-(((BENZYLOXY)CARBONYL)AMINO)-3-METHYLBUTANOATE;4-Nitrophenyl N-[(benzyloxy)carbonyl]-L-valinate;zvalonp;Z-L-Val-(p-Nitrophenyl)OH;Cbz-valine p-nitrophenyl ester;SCHEMBL7328473;CHEMBL3278835;DTXSID30146960;MFCD00038116;AKOS016003334;FD21109;HY-W142142;Z-Val-ONp, >=96.0% (TLC);AS-48961;CS-0201925;benzyloxycarbonyl-L-valine p-nitrophenyl ester;A896070;L-Valine,N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester;(S)-4-nitrophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate;L-Valine, N-((phenylmethoxy)carbonyl)-, 4-nitrophenyl ester;N-alpha-BenZyloxycarbonyl-L-valine p-nitrophenyl ester (CbZ-L-Val-ONp)

Suppliers and Price of 4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-L-valine 4-nitrophenyl ester
25g
$ 366.00

TRC
Z-Val-ONp
100mg
$ 60.00

Sigma-Aldrich
Z-Val-ONp ≥96.0% (TLC)
5g
$ 60.40

Iris Biotech GmbH
Z-L-Val-ONp
25 g
$ 168.75

Iris Biotech GmbH
Z-L-Val-ONp
5 g
$ 67.50

Crysdot
Z-Val-ONp 95+%
500g
$ 547.00

Chem-Impex
Z-L-valine4-nitrophenylester,99%(HPLC) 99%(HPLC)
25G
$ 56.00

Chem-Impex
Z-L-valine4-nitrophenylester,99%(HPLC) 99%(HPLC)
5G
$ 16.80

Chem-Impex
Z-L-valine 4-nitrophenyl ester ≥ 99% (HPLC)
100G
$ 165.00

Chemenu
Z-Val-ONp 95%
500g
$ 511.00

Total 25 raw suppliers

Chemical Property of 4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate

Chemical Property:

Vapor Pressure:2.95E-12mmHg at 25°C
Melting Point:61 °C
Boiling Point:552.6°Cat760mmHg
PKA:10.57±0.46(Predicted)
Flash Point:288°C
PSA：110.45000
Density:1.261g/cm³
LogP:4.36530
Storage Temp.:2-8°C
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:372.13213636
Heavy Atom Count:27
Complexity:505

Purity/Quality:

97% ^*data from raw suppliers

Z-L-valine 4-nitrophenyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)C(C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)[C@@H](C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)OCC2=CC=CC=C2

Technology Process of 4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate

There total 5 articles about 4-Nitrophenyl N-((benzyloxy)carbonyl)-L-valinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 10512-93-3
Z-Val-ONp

Guidance literature:: With N-ethylmorpholine;; hexamethylphosphorous triamide dichloride; In dichloromethane; 1) 0 deg C, 2 h, 2) overnight, r.t.;

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 10512-93-3
Z-Val-ONp

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; diethyl ether; pyridine

2: pyridine

With pyridine; thionyl chloride; diethyl ether;
DOI:10.1002/hlca.19570400216