3-((2-Ethoxyphenoxy)methyl)-3-piperidinol

Base Information

Chemical Name:3-((2-Ethoxyphenoxy)methyl)-3-piperidinol
CAS No.:104778-52-1
Molecular Formula:C14H21 N O3
Molecular Weight:251.326
Hs Code.:
DSSTox Substance ID:DTXSID60909202
ChEMBL ID:CHEMBL553797
Mol file:104778-52-1.mol

Synonyms:BRN 6061518;3-((2-Ethoxyphenoxy)methyl)-3-piperidinol;3-Piperidinol, 3-((2-ethoxyphenoxy)methyl)-;104778-52-1;3-[(2-ethoxyphenoxy)methyl]piperidin-3-ol;CHEMBL553797;DTXSID60909202;LS-117068

Suppliers and Price of 3-((2-Ethoxyphenoxy)methyl)-3-piperidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-((2-Ethoxyphenoxy)methyl)-3-piperidinol

Chemical Property:

Vapor Pressure:1.1E-06mmHg at 25°C
Boiling Point:387.1°Cat760mmHg
Flash Point:187.9°C
Density:1.102g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:251.15214353
Heavy Atom Count:18
Complexity:249

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=CC=C1OCC2(CCCNC2)O

Technology Process of 3-((2-Ethoxyphenoxy)methyl)-3-piperidinol

There total 4 articles about 3-((2-Ethoxyphenoxy)methyl)-3-piperidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 104778-55-4
1-benzyl-3-<(2-ethoxyphenoxy)methyl>-3-piperidinol

: 104778-52-1
3-<(2-ethoxyphenoxy)methyl>-3-piperidinol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;
DOI:10.1021/jm00384a040

Reference yield:

: 94-71-3
2-Ethoxyphenol

: 104778-52-1
3-<(2-ethoxyphenoxy)methyl>-3-piperidinol

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / NaOH / dioxane / 6 h / 110 °C

2: 92 percent / H₂ / 10percent Pd/C / ethanol / 760 Torr

With sodium hydroxide; hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethanol;
DOI:10.1021/jm00384a040

Reference yield:

: 40114-49-6
1-benzyl-3-piperidone

: 104778-52-1
3-<(2-ethoxyphenoxy)methyl>-3-piperidinol

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / dimethylsulfoxide / a) RT, 6 h, b) 50 deg C, 40 min

2: 68 percent / NaOH / dioxane / 6 h / 110 °C

3: 92 percent / H₂ / 10percent Pd/C / ethanol / 760 Torr

With sodium hydroxide; hydrogen; palladium on activated charcoal; In 1,4-dioxane; ethanol; dimethyl sulfoxide;
DOI:10.1021/jm00384a040