Prostan-1-oic acid, 15-hydroxy-9-oxo-, (15S)-

Base Information

• Chemical Name: Prostan-1-oic acid, 15-hydroxy-9-oxo-, (15S)-
• CAS No.: 37786-01-9
• Molecular Formula: C20H36O4
• Molecular Weight: 340.4974
• DSSTox Substance ID: DTXSID90191234
• Nikkaji Number: J386.544D
• Wikidata: Q83063755
• ChEMBL ID: CHEMBL3248898
• Mol file: 37786-01-9.mol

Synonyms:AY 23626;AY-23626;AY23626

Chemical Property of Prostan-1-oic acid, 15-hydroxy-9-oxo-, (15S)-

Chemical Property:

• Vapor Pressure: 3.09E-12mmHg at 25°C
• Boiling Point: 503.3°Cat760mmHg
• Flash Point: 272.2°C
• PSA: 74.60000
• Density: 1.018g/cm³
• LogP: 4.72830
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 14
• Exact Mass: 340.26135963
• Heavy Atom Count: 24
• Complexity: 367

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(CCC1CCC(=O)C1CCCCCCC(=O)O)O
• Isomeric SMILES: CCCCC[C@@H](CC[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)O)O

Technology Process of Prostan-1-oic acid, 15-hydroxy-9-oxo-, (15S)-

There total 9 articles about Prostan-1-oic acid, 15-hydroxy-9-oxo-, (15S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

15α-hydroxy-11-deoxy-8α,12β-prostaglandin-E1 (34603-80-0) → (+/-)-13.14-Dihydro-11-deoxy-PGE(1) (24341-38-6,25140-30-1,25488-93-1,37786-01-9,41100-55-4,50266-03-0,59780-42-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

Reference yield:

(+/-)-15-epi-11-deoxyprostaglandin E1 (21269-27-2,30194-23-1,34603-80-0,37786-00-8,38380-61-9,39765-01-0,39765-13-4,39765-14-5,40098-34-8,41264-02-2,41692-82-4,41692-88-0,41692-89-1,52485-21-9,52485-24-2,52521-56-9,52521-58-1,53403-52-4,63229-83-4,95341-50-7,117182-90-8,135970-46-6) → (+/-)-15-epi-13.14-Dihydro-11-deoxy-PGE(1) (24341-38-6,25140-30-1,25488-93-1,37786-01-9,41100-55-4,50266-03-0,59780-42-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

Reference yield:

(E)-1-[(6R,7R)-6-(7-Hydroxy-heptyl)-1,4-dioxa-spiro[4.4]non-7-yl]-oct-1-en-3-one → (+/-)-13.14-Dihydro-11-deoxy-PGE(1) (24341-38-6,25140-30-1,25488-93-1,37786-01-9,41100-55-4,50266-03-0,59780-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) CrO₃, H₂SO₄, DMF, (ii) KBH₄, sodium citrate, MeOH, (iii) aq. HCl

2: H₂ / Pd-C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol;

upstream raw materials:

15α-hydroxy-11-deoxy-8α,12β-prostaglandin-E₁

(+/-)-15-epi-11-deoxyprostaglandin E₁