34603-80-0

Upstream product

• 52477-97-1 2-(7-butoxycarbonylhexyl)-2-cyclopenten-1-one 
• 42542-00-7 (S)-3-(1-ethoxy-ethoxy)-1t-iodo-oct-1-ene 
• 34546-57-1 2-(6-methoxycarbonylhexyl)cyclopent-2-en-1-one 
• 50999-74-1 2-(6-Oxiranyl-hexyl)-cyclopent-2-enone 
• 32556-71-1 1-octyn-3-ol 
• 5239-43-0 7-(5-oxo-1-cyclopenten-1-yl)heptanoic acid 
• 39647-93-3 (S)-(E)-(+)-1-Iodo-1-octen-3-ol 
• 57378-32-2 15α-hydroxy-11-deoxyprostaglandin-E₁ ethyl ester 
• 20721-87-3 (+/-)-15-epi-11-deoxy PGE₁ methyl ester 
• 39198-04-4 (E)-1-chloro-oct-1-en-3-one 
• 39178-65-9 (E)-1-iodooct-1-en-3-ol 
• 39178-64-8 (E)-1-iodo-1-octen-3-one 
• 52487-91-9 1-iodo-3-(p-anisyldiphenylmethoxy)-trans-1-octene 
• 23472-43-7 7-[(1S,2R)-2-((E)-(R)-3-Acetoxy-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester 

Downstream Products

• 24341-38-6 (+/-)-13.14-Dihydro-11-deoxy-PGE(1) 
• 5239-90-7 11-deoxy-PGF_1α 
• 5239-90-7 11-deoxy PGF_1β 
• 21269-27-2 15α-hydroxy-11-deoxy-8β,12β-prostaglandin-E₁ 
• 24341-38-6 (+/-)-15-epi-13.14-Dihydro-11-deoxy-PGE(1) 
• 5239-90-7 (+/-)-15-epi-11-deoxyprostaglandin F_1α 
• 5239-90-7 (+/-)-15-epi-11-deoxyprostaglandin F_1β 

Relevant academic research and scientific papers

CONDENSATION OF ALLYL SULFOXIDES WITH CYCLOPENTENONES IN THE SYNTHESIS OF PROSTAGLANDINS. STEREOSPECIFIC TOTAL SYNTHESIS OF 11-DEOXYPROSTAGLANDIN-E1

The reactions of the vinyl sulfoxide group in the products from the addition of the carbanions of allyl sulfoxides to cyclopentenones were investigated.The α-alkylated vinyl sulfoxide is converted

TOTAL SYNTHESIS AND PROPERTIES OF PROSTAGLANDINS. VII.* ISOMERIZATION OF(+/-)-11-DEOXYPROSTAGLANDIN-E1

Under equilibrium conditions (+/-)-11-deoxyprotaglandin-E1 exists in the form of a mixture of the 8,12-cis and 8,12-trans-isomers with a preponderance of the thermodynamically more favorable trans isomer.The 8-epimers can be converted into each other and are separated preparatively by crystallization or by chromatogratic methods.During exhaustive silylation of the isomers the same 1,9,15-tris-O-silyl derivative with an enolic C=C double bond at positions 8,9 is formed.

15-Substituted prostanoic acids

9-Oxo-15-Substituted prostanoic acids, and intermediates for their preparation are disclosed. The final products have bronchodilatory activity.

Novel 11-hydroxy-9-keto-5,6-cis-13,14-cis-prostadienoic acid derivatives

This disclosure describes certain 11-hydroxy and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents, or as intermediates.

Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates

This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.

2-Substituted-3,4-epoxycyclopentan-1-ones, and 2-substituted-3,4-epoxycyclopentan-1-ols

This disclosure describes 2-substituted-3,4-epoxy-cyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.