1-(Difluoromethoxy)-1,2,2-trifluoroethane

Base Information

• Chemical Name: 1-(Difluoromethoxy)-1,2,2-trifluoroethane
• CAS No.: 60113-74-8
• Molecular Formula: C3H3 F5 O
• Molecular Weight: 150.048
• Hs Code.: 2909199090
• European Community (EC) Number: 262-063-2
• DSSTox Substance ID: DTXSID30971719
• Nikkaji Number: J298.781C
• Mol file: 60113-74-8.mol

Synonyms:1-(Difluoromethoxy)-1,2,2-trifluoroethane;60113-74-8;EINECS 262-063-2;56281-92-6;SCHEMBL499006;DTXSID30971719

Chemical Property of 1-(Difluoromethoxy)-1,2,2-trifluoroethane

Chemical Property:

• Vapor Pressure: 533mmHg at 25°C
• Boiling Point: 34.9°C at 760 mmHg
• PSA: 9.23000
• Density: 1.33g/cm³
• LogP: 1.78630
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 150.01040553
• Heavy Atom Count: 9
• Complexity: 74.6

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(F)F)(OC(F)F)F

Technology Process of 1-(Difluoromethoxy)-1,2,2-trifluoroethane

There total 6 articles about 1-(Difluoromethoxy)-1,2,2-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

enflurane → 1,2,2-trifluoroethyl difluoromethyl ether (60113-74-8)

Guidance literature:

palladium; In acetone;

Reference yield: 40.0%

1-bromo-1,2,2-trifluoroethyl difluoromethyl ether + 2-bromo-1,2,2-trifluoroethyl difluoromethyl ether → 1,2,2-trifluoroethyl difluoromethyl ether (60113-74-8)

Guidance literature:

palladium; In acetone;

Reference yield:

2-Chloro-1,2,2-trifluoroethyl difluoromethyl ether (35412-71-6) → 1,2,2-trifluoroethyl difluoromethyl ether (60113-74-8)

Guidance literature:

In methanol;

upstream raw materials:

2-Chloro-1,2,2-trifluoroethyl difluoromethyl ether

zinc