3-(3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-5-[(Z)-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)methylene]-4-hydroxy-2(5H)-furanone

Base Information

• Chemical Name: 3-(3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-5-[(Z)-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)methylene]-4-hydroxy-2(5H)-furanone
• CAS No.: 55215-32-2
• Molecular Formula: C27H28O5
• Molecular Weight: 432.51
• Mol file: 55215-32-2.mol

Synonyms:Aspulvinone A;3-(2,2-Dimethyl-chroman-6-yl)-5-[1-(2,2-dimethyl-chroman-6-yl)-meth-(Z)-ylidene]-4-hydroxy-5H-furan-2-one;

Chemical Property of 3-(3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-5-[(Z)-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)methylene]-4-hydroxy-2(5H)-furanone

Chemical Property:

• PSA: 64.99000
• LogP: 5.76080

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-5-[(Z)-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)methylene]-4-hydroxy-2(5H)-furanone

There total 5 articles about 3-(3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-5-[(Z)-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)methylene]-4-hydroxy-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,2,2-trifluoroethyl (Z)-3-(2,2-dimethylchroman-6-yl)-2-[(2,2-dimethylchroman-6-yl)acetoxy]acrylate → Aspulvinone A (55215-32-2)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

DOI:10.1055/s-2007-983803

Reference yield: 89.0%

(Z)-5-[(2,2-dimethylchroman-6-yl)methylene]-4-hydroxy-3-[4-methoxy-3-(3-methylbut-2-enyl)phenyl]furan-2(5H)-one → Aspulvinone A (55215-32-2)

Guidance literature:

With boron tribromide; In hexane; dichloromethane; at -78 ℃;

DOI:10.1055/s-2007-983803

Reference yield: 60.0%

2,2-dimethylchroman (1198-96-5) + (Z)-3-diazo-5-((2,2-dimethylchroman-6-yl)methylene)furan-2,4(3H,5H)-dione → Aspulvinone A (55215-32-2)

Guidance literature:

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; at 50 ℃; for 6h; Inert atmosphere;

DOI:10.1039/c8ob01511b

upstream raw materials:

2,2-dimethylchroman