Benzene-1,2,4,5-tetracarboxamide

Base Information

• Chemical Name: Benzene-1,2,4,5-tetracarboxamide
• CAS No.: 6183-35-3
• Molecular Formula: C10H10 N4 O4
• Molecular Weight: 250.214
• Hs Code.: 2924299090
• NSC Number: 94777
• UNII: 7V6C2CZ9GM
• DSSTox Substance ID: DTXSID80294147
• Wikidata: Q82033259
• Mol file: 6183-35-3.mol

Synonyms:benzene-1,2,4,5-tetracarboxamide;6183-35-3;1,2,4,5-Benzenetetracarboxamide;Pyromellitamide;NSC-94777;7V6C2CZ9GM;NSC94777;UNII-7V6C2CZ9GM;NCIOpen2_005822;1,4,5-Benzenetetracarboxamide;SCHEMBL1222250;DTXSID80294147;AKOS015889519;1,2,4,5-Benzenetetracarboxamide, 97%;BS-49255;E75055;SR-01000197752;SR-01000197752-1

Chemical Property of Benzene-1,2,4,5-tetracarboxamide

Chemical Property:

• Vapor Pressure: 8.33E-11mmHg at 25°C
• Melting Point: >300 °C(lit.)
• Boiling Point: 517.3°C at 760 mmHg
• PKA: 14.12±0.50(Predicted)
• Flash Point: 266.6°C
• PSA: 172.36000
• Density: 1.523g/cm³
• LogP: 0.88340
• XLogP3: -2.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 250.07020481
• Heavy Atom Count: 18
• Complexity: 335

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2,4,5-Benzenetetracarboxamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1C(=O)N)C(=O)N)C(=O)N)C(=O)N

Technology Process of Benzene-1,2,4,5-tetracarboxamide

There total 6 articles about Benzene-1,2,4,5-tetracarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

pyrrolo[3,4-f]isoindole-1,3,5,7-tetraone (2550-73-4) → 1,2,4,5-Benzenetetracarboxylic acid tetraamide (6183-35-3)

Guidance literature:

With ammonium hydroxide; Ambient temperature;

Reference yield: 60.0%

1,2,4,5-benzenetetracarboxylic acid (89-05-4) → 1,2,4,5-Benzenetetracarboxylic acid tetraamide (6183-35-3)

Guidance literature:

With ammonium hydroxide; urea; In water; 1) 135-140 deg C, 2) cooling, 1.5 h;

DOI:10.1021/jo00037a020

Reference yield:

Pyromellitic dianhydride (89-32-7,34527-94-1) → 1,2,4,5-Benzenetetracarboxylic acid tetraamide (6183-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: urea / various solvent(s) / 1.) 140 deg C, 4 h, 2.) 160 deg C, 2 h

2: conc. aq. NH₃ / 16 h

With ammonium hydroxide; urea; In various solvent(s);

upstream raw materials:

1,2,4,5-benzenetetracarboxylic acid

pyrrolo[3,4-f]isoindole-1,3,5,7-tetraone

urea

Pyromellitic dianhydride

Downstream raw materials:

2-(2,4,5-Tricyanophenyl)-1,3-dioxolane

5,6-dicyano-3-hydroxy-3-(diphenylmethyl)-2-methylisoindol-1-one

1,1,2,2-tetraphenylethane

Refernces

• 1、 -. "Corresponding amine nitrile and method of manufacturing thereof". Paragraph 0122; 0123; 0127; 0129. . Retrieved 2018/05/24.
• 2、 Freccero, Mauro,Fasani, Elisa,Albini, Angelo. "Photochemical Reaction of Phthalimides and Dicyanophthalimides with Benzylic Donors". . p. 1740 - 1745. Retrieved 2007/10/02.