2-Hydroxy-N'-(2-hydroxybenzoyl)benzohydrazide

Base Information

• Chemical Name: 2-Hydroxy-N'-(2-hydroxybenzoyl)benzohydrazide
• CAS No.: 23647-78-1
• Molecular Formula: C14H12 N2 O4
• Molecular Weight: 272.26
• Hs Code.: 2928000090
• European Community (EC) Number: 245-804-4
• NSC Number: 691999,408200
• UNII: D9R89W89CJ
• DSSTox Substance ID: DTXSID80178317
• Nikkaji Number: J30.051I
• Wikidata: Q83048708
• ChEMBL ID: CHEMBL36303
• Mol file: 23647-78-1.mol

Synonyms:N,N'-bis(salicyl)hydrazine;N,N'-bis-salicylhydrazine;N,N'-disalicylhydrazine

Chemical Property of 2-Hydroxy-N'-(2-hydroxybenzoyl)benzohydrazide

Chemical Property:

• Vapor Pressure: 8.67E-15mmHg at 25°C
• Boiling Point: 595.7°Cat760mmHg
• Flash Point: 314.1°C
• PSA: 98.66000
• Density: 1.397g/cm³
• LogP: 1.95440
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 272.07970687
• Heavy Atom Count: 20
• Complexity: 327

Purity/Quality:

99% ^*data from raw suppliers

2-HYDROXY-N'-(2-HYDROXYBENZOYL)BENZOHYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)NNC(=O)C2=CC=CC=C2O)O

Technology Process of 2-Hydroxy-N'-(2-hydroxybenzoyl)benzohydrazide

There total 14 articles about 2-Hydroxy-N'-(2-hydroxybenzoyl)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

salicylic acid pentafluorophenyl ester (187806-42-4) → N,N'-bis(salicyloyl)hydrazine (23647-78-1)

Guidance literature:

With hydrazine hydrate; In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1016/S0040-4020(97)00149-X

Reference yield: 91.0%

2-Hydroxybenzoylhydrazine (936-02-7) + salicylic acid pentafluorophenyl ester (187806-42-4) → N,N'-bis(salicyloyl)hydrazine (23647-78-1)

Guidance literature:

In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1016/S0040-4020(97)00149-X

Reference yield: 86.0%

2-Hydroxybenzoylhydrazine (936-02-7) → N-(3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-benzamide (109702-97-8) + N,N'-bis(salicyloyl)hydrazine (23647-78-1)

Guidance literature:

With 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one; In 1,4-dioxane; for 2h; Heating;

DOI:10.1039/a803973i

upstream raw materials:

2-Hydroxybenzoylhydrazine

salicylic acid pentafluorophenyl ester

sulfuric acid

1,1-bis(benzotriazene-4-one)

Downstream raw materials:

2,5-bis(2-hydroxyphenyl)-1,3,4-oxadiazole