2-HYDROXY-1-(4-HYDROXY-PHENYL)-ETHANONE

Base Information

• Chemical Name: 2-HYDROXY-1-(4-HYDROXY-PHENYL)-ETHANONE
• CAS No.: 2491-39-6
• Molecular Formula: C8H7BrO3
• Molecular Weight: 231.046
• Hs Code.: 2914700090
• Mol file: 2491-39-6.mol

Synonyms:Acetophenone,2-bromo-2',4'-dihydroxy- (7CI,8CI);1-(2,4-Dihydroxyphenyl)-2-bromoethanone;2-Bromo-2',4'-dihydroxyacetophenone;

Chemical Property of 2-HYDROXY-1-(4-HYDROXY-PHENYL)-ETHANONE

Chemical Property:

• Vapor Pressure: 6.56E-06mmHg at 25°C
• Melting Point: 128-132 °C(lit.)
• Refractive Index: 1.649
• Boiling Point: 367.212 °C at 760 mmHg
• PKA: 7.28±0.35(Predicted)
• Flash Point: 175.9 °C
• PSA: 57.53000
• Density: 1.764 g/cm³
• LogP: 1.67540

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-2',4'-dihydroxyacetophenone >97.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 22-34-43
• Safety Statements: 26-36/37/39-45

MSDS Files:

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-HYDROXY-1-(4-HYDROXY-PHENYL)-ETHANONE

There total 6 articles about 2-HYDROXY-1-(4-HYDROXY-PHENYL)-ETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ 2-bromo-2',4'-dihydroxyoacetophenone (2491-39-6)

Guidance literature:

Reference yield: 88.0%

2',4'-dihydroxy-4-acetophenone (89-84-9) → 2-bromo-2',4'-dihydroxyoacetophenone (2491-39-6)

Guidance literature:

With aluminium trichloride; Montmorillonite K₁₀; bromine; In ethyl acetate; at 20 ℃; for 2h;

Reference yield:

2',4'-dihydroxy-2-bromoacetophenone → 2-bromo-2',4'-dihydroxyoacetophenone (2491-39-6)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 1h;

DOI:10.1016/j.ejmech.2015.02.055

upstream raw materials:

recorcinol

cyanomethyl bromide

2',4'-dihydroxy-4-acetophenone

2-Bromoacetyl bromide

Downstream raw materials:

4-(2-(4-hydroxyphenylamino)thiazol-4-yl)benzene-1,3-diol

4-(2-(2-hydroxyphenylamino)thiazol-4-yl)benzene-1,3-diol

4-(2-(3-hydroxyphenylamino)thiazol-4-yl)benzene-1,3-diol

4-(2-(phenylamino)thiazol-4-yl)benzene-1,3-diol