8-Vinyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-2-naphthalenecarbaldehyde

Base Information

Chemical Name:8-Vinyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-2-naphthalenecarbaldehyde
CAS No.:2221-68-3
Molecular Formula:C₁₄H₁₈O
Molecular Weight:202.296
Hs Code.:
Mol file:2221-68-3.mol

Synonyms:2-Naphthaldehyde,3,4,4ab,5,6,7,8,8aa-octahydro-5-methylene-8-vinyl-(7CI,8CI); 2-Naphthalenecarboxaldehyde,8-ethenyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-, [4aS-(4aa,8b,8ab)]-; Khusilal

Suppliers and Price of 8-Vinyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-2-naphthalenecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of 8-Vinyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-2-naphthalenecarbaldehyde

Chemical Property:

PSA：17.07000
LogP:3.29010

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-Vinyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-2-naphthalenecarbaldehyde

There total 10 articles about 8-Vinyl-3,4,4a,5,6,7,8,8a-octahydro-5-methylene-2-naphthalenecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121666-50-0
4-acetylhex-3-enone 1-ethylene ketal

: 2221-68-3,127128-55-6
(+/-)-khusilal

Guidance literature:: Multi-step reaction with 9 steps

1: 1.) LDA / 1.) THF, -85 deg C, 30 min, 2.) 1 h

2: 1.) MeLi / 1.) THF, room temperature, 30 min, 2.) room temperature, overnight

3: 1.) NaH, MeOH / 1.) 40 deg C, 4.4 h

4: 94 percent / tetrahydrofuran / 0.5 h

5: LiAlH₄ / tetrahydrofuran / 0.42 h

6: (COCl)2, DMSO, Et₃N / CH₂Cl₂

7: tetrahydrofuran / 0.17 h

8: 80 percent / PPTS / acetone; H₂O / 22 h / Heating

9: 1.) BuLi, 2.) LiClO₄, CaCO₃ / 1.) THF, -95 deg C -> room temperature, 2 h; reflux, 1.5 h, 2.) HMPA, 130 deg C, 1 h

With methanol; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; methyllithium; lithium perchlorate; pyridinium p-toluenesulfonate; sodium hydride; dimethyl sulfoxide; triethylamine; calcium carbonate; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; water; acetone;

Reference yield:

: 121666-58-8
methyl 7-ethylenedioxydecahydro-4-oxo-1-(trimethylsilyl)naphthalene-1-carboxylate

: 2221-68-3,127128-55-6
(+/-)-khusilal

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) NaH, MeOH / 1.) 40 deg C, 4.4 h

2: 94 percent / tetrahydrofuran / 0.5 h

3: LiAlH₄ / tetrahydrofuran / 0.42 h

4: (COCl)2, DMSO, Et₃N / CH₂Cl₂

5: tetrahydrofuran / 0.17 h

6: 80 percent / PPTS / acetone; H₂O / 22 h / Heating

7: 1.) BuLi, 2.) LiClO₄, CaCO₃ / 1.) THF, -95 deg C -> room temperature, 2 h; reflux, 1.5 h, 2.) HMPA, 130 deg C, 1 h

With methanol; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; lithium perchlorate; pyridinium p-toluenesulfonate; sodium hydride; dimethyl sulfoxide; triethylamine; calcium carbonate; In tetrahydrofuran; dichloromethane; water; acetone;

Reference yield:

: 127075-61-0
3,4,4aβ,5,6,7,8,8aα-octahydro-5-methylene-8α-vinylnaphthalen-2(1H)-one ethylene ketal

: 2221-68-3,127128-55-6
(+/-)-khusilal

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / PPTS / acetone; H₂O / 22 h / Heating

2: 1.) BuLi, 2.) LiClO₄, CaCO₃ / 1.) THF, -95 deg C -> room temperature, 2 h; reflux, 1.5 h, 2.) HMPA, 130 deg C, 1 h

With n-butyllithium; lithium perchlorate; pyridinium p-toluenesulfonate; calcium carbonate; In water; acetone;