Methylene Chloride

Base Information

• Chemical Name: Methylene Chloride
• CAS No.: 75-09-2
• Deprecated CAS: 1173020-57-9
• Molecular Formula: CH2Cl2
• Molecular Weight: 84.9329
• Hs Code.: 2903.12
• European Community (EC) Number: 200-838-9
• ICSC Number: 0058
• NSC Number: 406122
• UN Number: 1593
• UNII: 588X2YUY0A
• DSSTox Substance ID: DTXSID0020868,DTXSID60166893
• Nikkaji Number: J2.389B
• Wikipedia: Dichloromethane
• Wikidata: Q421748,Q425210,Q83060108
• NCI Thesaurus Code: C44400
• RXCUI: 1311537
• Metabolomics Workbench ID: 44945
• ChEMBL ID: CHEMBL45967
• Mol file: 75-09-2.mol

Synonyms:Bichloride, Methylene;Chloride, Methylene;Dichloride, Methylene;Dichloromethane;Methylene Bichloride;Methylene Chloride;Methylene Dichloride;Solaesthin

Chemical Property of Methylene Chloride

Chemical Property:

• Appearance/Colour: colorless liquid
• Melting Point: -97 °C
• Refractive Index: 1.4242
• Boiling Point: 39.6 °C at 760 mmHg
• Flash Point: 39-40 °C
• PSA: 0.00000
• Density: 1.252 g/cm³
• LogP: 1.42150
• Water Solubility.: 20 g/L (20℃)
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 83.9533555
• Heavy Atom Count: 3
• Complexity: 2.8
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn,T,F
• Hazard Codes: Xn:Harmful
• Statements: R40:
• Safety Statements: S23:; S24/25:; S36/37:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Chlorinated Aliphatics
• Canonical SMILES: C(Cl)Cl
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. The substance may cause effects on the central nervous system, blood, liver, heart and lungs. Exposure could cause carbon monoxide poisoning. This may result in impaired functions. Exposure at high concentrations could cause lowering of consciousness and death. The effects may be delayed.
• Effects of Long Term Exposure: The substance may have effects on the central nervous system. This substance is probably carcinogenic to humans.

Technology Process of Methylene Chloride

There total 219 articles about Methylene Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

methane (34557-54-5,27936-85-2) → tetrachloromethane (56-23-5) + methylene chloride (74-87-3) + dichloromethane (75-09-2) + chloroform (67-66-3,8013-54-5) + methanesulfonyl chloride (124-63-0)

Guidance literature:

With hydrogenchloride; sulfur dioxide; chlorine; at 63 - 67 ℃; under 6750.68 Torr; Photolysis;

Reference yield: 54.9%

methane (34557-54-5,27936-85-2) → dichloromethane (75-09-2) + chloroform (67-66-3,8013-54-5) + methanesulfonyl chloride (124-63-0)

Guidance literature:

With sulfur dioxide; chlorine; at 65 ℃; for 1h; under 2250.23 Torr; Temperature; Irradiation;

Reference yield: 52.0%

tetrachloromethane (56-23-5) → dichloromethane (75-09-2) + chloroform (67-66-3,8013-54-5)

Guidance literature:

With tetra-n-butylphosphonium formate; In water; at -20 - 22 ℃; for 1.33333h; Reagent/catalyst;

upstream raw materials:

tetrachloromethane

methylene chloride

diiodomethane

tert-butylhypochlorite

Downstream raw materials:

Vinyl sulfonic acid methyl ester

1,1'-bis(imidazolyl)methane

β-Chlor-α-phenyl-α-methylthio-ethan

1-chloro-2-methylthio-1-phenylethane

Refernces

• 1、 Sonoyama, Noriyuki,Hara, Kohjiro,Sakata, Tadayoshi. "Reductive electrochemical decomposition of chloroform on metal electrodes". . p. 131 - 132. Retrieved 1997.
• 2、 Lytvynenko,Kolotilov,Kiskin,Cador,Golhen,Aleksandrov,Mishura,Titov,Ouahab,Eremenko,Novotortsev. "Redox-active porous coordination polymers prepared by trinuclear heterometallic pivalate linking with the redox-active nickel(II) complex: Synthesis, structure, magnetic and redox properties, and electrocatalytic activity in organic compound dehalogenation in heterogeneous medium". . p. 4970 - 4979. Retrieved 2014.
• 3、 -. "CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA". . . Retrieved 2022/01/12.
• 4、 -. "Method of Converting a Brominated Hydrocarbon to a Chlorinated Hydrocarbon". Paragraph 0183-0186. . Retrieved 2021/02/19.