N-(p-Chlorophenyl)-2-methoxy-6-methylnicotinamidine

Base Information

• Chemical Name: N-(p-Chlorophenyl)-2-methoxy-6-methylnicotinamidine
• CAS No.: 85606-01-5
• Molecular Formula: C₁₄H₁₄ClN₃O
• Molecular Weight: 275.738
• DSSTox Substance ID: DTXSID301006185
• Mol file: 85606-01-5.mol

Synonyms:N-(p-Chlorophenyl)-2-methoxy-6-methylnicotinamidine;Nicotinamidine, N-(p-chlorophenyl)-2-methoxy-6-methyl-;85606-01-5;3-Pyridinecarboximidamide, N-(4-chlorophenyl)-2-methoxy-6-methyl-;DTXSID301006185;N'-(4-chlorophenyl)-2-methoxy-6-methylpyridine-3-carboximidamide;LS-96468

Chemical Property of N-(p-Chlorophenyl)-2-methoxy-6-methylnicotinamidine

Chemical Property:

• Boiling Point: 430.7°Cat760mmHg
• Flash Point: 214.3°C
• Density: 1.24g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 275.0825398
• Heavy Atom Count: 19
• Complexity: 316

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC(=C(C=C1)C(=NC2=CC=C(C=C2)Cl)N)OC

Technology Process of N-(p-Chlorophenyl)-2-methoxy-6-methylnicotinamidine

There total 1 articles about N-(p-Chlorophenyl)-2-methoxy-6-methylnicotinamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-methoxy-6-methylpyridine-3-carbonitrile (72918-03-7) + C6H4ClN(2-)*2Br(1-)*2Mg(2+) → N-(4-Chloro-phenyl)-2-methoxy-6-methyl-nicotinamidine (85606-01-5)

Guidance literature:

In diethyl ether; for 3h; Heating;

DOI:10.1007/BF00765211

Reference yield: 48.0%

N-(4-Chloro-phenyl)-2-methoxy-6-methyl-nicotinamidine (85606-01-5) + oxalic acid diethyl ester (95-92-1) → N-[[(Z)-4-Chloro-phenylimino]-(2-methoxy-6-methyl-pyridin-3-yl)-methyl]-oxalamic acid ethyl ester (85606-06-0)

Guidance literature:

In ethanol; for 10h; Heating;

DOI:10.1007/BF00765211

upstream raw materials:

2-methoxy-6-methylpyridine-3-carbonitrile

Downstream raw materials:

N-[[(Z)-4-Chloro-phenylimino]-(2-methoxy-6-methyl-pyridin-3-yl)-methyl]-oxalamic acid ethyl ester