Carmellose sodium

Base Information

• Chemical Name: Carmellose sodium
• CAS No.: 74811-65-7
• Deprecated CAS: 117385-93-0,12624-09-8,198084-97-8,37231-14-4,37231-15-5,50642-44-9,54018-17-6,55607-96-0,73699-63-5,80296-93-1,81209-86-1,82197-79-3,9045-95-8,9085-26-1,247080-55-3,404943-62-0,454679-81-3,64103-90-8,654655-39-7,1012064-31-1,1262215-38-2,147881-80-9,854036-84-3,1296213-64-3,1422717-46-1,1428980-42-0,1610028-94-8,1610029-04-3,2014388-59-9,2072854-79-4,2131127-75-6,2228913-23-1,2229957-39-3,2260925-91-3,2416156-06-2,2459461-90-4,2492491-76-4,2715109-01-4
• Molecular Formula: Null
• European Community (EC) Number: 618-378-6,629-739-2
• NCI Thesaurus Code: C80923,C83596
• RXCUI: 491498,1310573,1371909,1653793,2257286,2475182,2565686,2584311,2625171,2632123
• Mol file: 74811-65-7.mol

Synonyms:Aquacel;Aquaplast;Carboxymethyl Cellulose;Carboxymethylcellulose;Carboxymethylcellulose Sodium;Carboxymethylcellulose, Sodium;carmellose sodium;Cellolax;Cellulose, Carboxymethyl;Cethylose;Croscarmellose Sodium;Polycell;Ruspol;Sodium Carboxymethylcellulose;Sodium, Carboxymethylcellulose;Sodium, Carmellose;Sodium, Croscarmellose

Chemical Property of Carmellose sodium

Chemical Property:

• Appearance/Colour: Free-flowing, fibrous powder
• PSA: 86.28000
• Density: Bulk density (g/cc) 0.48
• LogP: -1.47370
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Practically insoluble in acetone, in anhydrous ethanol and in toluene.
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 263.07428675
• Heavy Atom Count: 17
• Complexity: 169

Purity/Quality:

98%min ^*data from raw suppliers

CroscarmelloseSodium ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Chemical Classes: Biological Agents -> Polysaccharides
• Canonical SMILES: CC(=O)O.C(C(C(C(C(C=O)O)O)O)O)O.[Na]
• Recent ClinicalTrials: Dry Eye Disease Study With Brimonidine
• Recent EU Clinical Trials: ANTIBIOTICS VERSUS PLACEBO FOR ACUTE BACTERIAL CONJUNCTIVITIS IN CHILDREN: A RANDOMISED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL
• Uses: Packaged under nitrogen Used as Disintegrant in Capsules, Tablet and Granule Formulations. Croscarmellose Sodiumis a super disintegrant used in pharmaceuticals in the synthesis of tablets for oral administration.

Technology Process of Carmellose sodium

There total 2 articles about Carmellose sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Croscarmellose sodium (74811-65-7)

Guidance literature:

Reference yield:

→ Croscarmellose sodium (74811-65-7) + sodium stearate (822-16-2)

Guidance literature:

Refernces

• 1、 -. "Multilayered tablet containing pravastatin and aspirin and method". . . Retrieved 2008/06/13.