2,3-Diphenylquinoxaline

Base Information

• Chemical Name: 2,3-Diphenylquinoxaline
• CAS No.: 1684-14-6
• Molecular Formula: C20H14N2
• Molecular Weight: 282.345
• Hs Code.: 29339900
• European Community (EC) Number: 216-865-4
• NSC Number: 15232
• UNII: 5MJ74FC4Q6
• DSSTox Substance ID: DTXSID70168560
• Nikkaji Number: J124.220B
• Wikidata: Q69758902
• ChEMBL ID: CHEMBL302245
• Mol file: 1684-14-6.mol

Synonyms:2,3-Diphenylquinoxaline;1684-14-6;QUINOXALINE, 2,3-DIPHENYL-;2,3-Diphenyl-quinoxaline;5MJ74FC4Q6;CHEMBL302245;2,3-Diphenyl-1,4-quinoxaline;EINECS 216-865-4;NSC-15232;AI3-23103;Quinoxaline,2,3-diphenyl-;NSC15232;2,3diphenylquinoxaline;2,3-Diphenylchinoxalin;Quinoxaline,3-diphenyl-;ChemDiv1_026460;UNII-5MJ74FC4Q6;Oprea1_201793;DivK1c_004204;SCHEMBL732131;HMS662C16;DTXSID70168560;BDBM50468942;MFCD00014659;NSC 15232;STK874237;AKOS000447185;CCG-244376;CDS1_003164;AS-37775;A3725;D2442;FT-0609739;AC-907/25014341;EN300-18202641;SR-01000554108;SR-01000554108-1;Z55175529

Chemical Property of 2,3-Diphenylquinoxaline

Chemical Property:

• Appearance/Colour: Light beige or grey solid
• Vapor Pressure: 9.88E-07mmHg at 25°C
• Melting Point: 125-128 °C
• Refractive Index: 1.666
• Boiling Point: 415.52 °C at 760 mmHg
• PKA: -0.06±0.48(Predicted)
• Flash Point: 175.889 °C
• PSA: 25.78000
• Density: 1.174 g/cm³
• LogP: 4.96380
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 282.115698455
• Heavy Atom Count: 22
• Complexity: 310

Purity/Quality:

97% ^*data from raw suppliers

2,3-Diphenylquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC3=CC=CC=C3N=C2C4=CC=CC=C4

Technology Process of 2,3-Diphenylquinoxaline

There total 94 articles about 2,3-Diphenylquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + 2-nitro-aniline (88-74-4) → 2,3-diphenylquinoxaline (1684-14-6) + benzil (134-81-6)

Guidance literature:

With sodium hydroxide; In toluene; at 120 ℃; for 3h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.0c02453

Reference yield: 98.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + 1,2-diamino-benzene (95-54-5) → 2,3-diphenylquinoxaline (1684-14-6)

Guidance literature:

With hexaammonium heptamolybdate tetrahydrate; at 90 ℃; for 0.25h; Concentration; Temperature; Reagent/catalyst; Time; Catalytic behavior; Microwave irradiation;

DOI:10.1016/j.crci.2012.06.007

Reference yield: 97.0%

2-nitro-aniline (88-74-4) + benzil (134-81-6) → 2,3-diphenylquinoxaline (1684-14-6)

Guidance literature:

With tin(ll) chloride; In ethanol; water; for 0.333333h; Reflux;

DOI:10.1002/jhet.5570450637

upstream raw materials:

1-Benzoyl-1-phenyl-2-piperidino-ethanol

1,2-diamino-benzene

1,3-dimethyl-4,5-diphenyl-4,5-dihydroxyimidazolidin-2-one

o-phenylenediamine hydrochloride

Downstream raw materials:

1,4-Dihydro-2,3-diphenylchinoxalin

2,3-diphenyl-1,2-dihydro-quinoxaline

(+)-trans-2,3-diphenyl-1,2,3,4-tetrahydro-quinoxaline

(-)-trans-2,3-diphenyl-1,2,3,4-tetrahydro-quinoxaline