Technology Process of 9-pentofuranosyl-9H-purine-6-carboxamide
There total 5 articles about 9-pentofuranosyl-9H-purine-6-carboxamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium hydroxide; dihydrogen peroxide;
In
methanol;
for 5h;
Ambient temperature;
DOI:10.1021/jm00136a008
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 83 percent / 1.0 N aq. NaOH / methanol / 0.25 h / Ambient temperature
2: 88.9 percent / 4-(N,N-dimethylamino)pyridine / 1.25 h / Ambient temperature
3: 80.5 percent / aq. KMnO4 / acetic acid / 1 h / 0 - 5 °C
4: 50 percent / dimethylformamide / 2.5 h / Ambient temperature
5: 50 percent / 30percent aq. H2O2, conc. NH4OH / methanol / 5 h / Ambient temperature
With
dmap; ammonium hydroxide; sodium hydroxide; potassium permanganate; dihydrogen peroxide;
In
methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00136a008
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 80.5 percent / aq. KMnO4 / acetic acid / 1 h / 0 - 5 °C
2: 50 percent / dimethylformamide / 2.5 h / Ambient temperature
3: 50 percent / 30percent aq. H2O2, conc. NH4OH / methanol / 5 h / Ambient temperature
With
ammonium hydroxide; potassium permanganate; dihydrogen peroxide;
In
methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00136a008
